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Machine translation
1. (WO2011143057) NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/143057    International Application No.:    PCT/US2011/035501
Publication Date: 17.11.2011 International Filing Date: 06.05.2011
IPC:
A01N 43/56 (2006.01), A61K 31/415 (2006.01)
Applicants: MERCK SHARP & DOHME CORP. [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US) (For All Designated States Except US).
HALE, Jeffrey, J. [US/US]; (US) (For US Only).
JIANG, Jinlong [US/US]; (US) (For US Only).
SHEN, Dong-Ming [US/US]; (US) (For US Only).
SHI, Zhi-Cai [US/US]; (US) (For US Only).
SHU, Min [US/US]; (US) (For US Only).
WU, Zhicai [US/US]; (US) (For US Only).
YANG, Cangming [US/US]; (US) (For US Only)
Inventors: HALE, Jeffrey, J.; (US).
JIANG, Jinlong; (US).
SHEN, Dong-Ming; (US).
SHI, Zhi-Cai; (US).
SHU, Min; (US).
WU, Zhicai; (US).
YANG, Cangming; (US)
Common
Representative:
MERCK SHARP & DOHME CORP.; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US)
Priority Data:
61/333,451 11.05.2010 US
Title (EN) NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS
(FR) INHIBITEURS INÉDITS DE LA PROLYLCARBOXYPEPTIDASE
Abstract: front page image
(EN)Compounds of structural formula I are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and treatment of conditions related to the enzymatic activity of PrCP such as abnormal metabolism, including obesity; diabetes; metabolic syndrome; obesity related disorders; and diabetes related disorders.
(FR)La présente invention concerne des composés de formule développée I qui sont des inhibiteurs de la prolylcarboxypeptidase (PrCP). Les composés de la présente invention peuvent être utilisés en vue de la prévention et du traitement d'affections associées à l'activité enzymatique de la PrCP, telles que les anomalies du métabolisme et notamment l'obésité, le diabète, le syndrome métabolique, les troubles associés à l'obésité et les troubles associés au diabète.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)