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1. (WO2011142865) YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/142865    International Application No.:    PCT/US2011/024482
Publication Date: 17.11.2011 International Filing Date: 11.02.2011
IPC:
C12N 1/00 (2006.01), C12N 15/74 (2006.01)
Applicants: GEVO, INC. [US/US]; 345 Inverness Drive South Building C, Suite 310 Englewood, CO 80112 (US) (For All Designated States Except US).
CALIFORNIA INSTITUTE OF TECHNOLOGY [US/US]; 1200 E. California Blvd. M/C 210-85 Pasadena, CA 91125 (US) (For All Designated States Except US).
BUELTER, Thomas [DE/US]; (US) (For US Only).
HAWKINS, Andrew [US/US]; (US) (For US Only).
PORTER-SCHEINMAN, Stephanie [US/US]; (US) (For US Only).
MEINHOLD, Peter [DE/US]; (US) (For US Only).
DUNDON, Catherine, Asleson [US/US]; (US) (For US Only).
ARISTIDOU, Aristos [CY/US]; (US) (For US Only).
URANO, Jun [US/US]; (US) (For US Only).
LIES, Doug [US/US]; (US) (For US Only).
PETERS, Matthew [US/US]; (US) (For US Only).
DEY, Melissa [US/US]; (US) (For US Only).
JANCAUSKAS, Justas [LT/US]; (US) (For US Only).
EVANS, Kent [US/US]; (US) (For US Only).
KELLY, Julie [US/US]; (US) (For US Only).
BERRY, Ruth [US/US]; (US) (For US Only).
BASTIAN, Sabine [DE/US]; (US) (For US Only).
ARNOLD, Frances [US/US]; (US) (For US Only)
Inventors: BUELTER, Thomas; (US).
HAWKINS, Andrew; (US).
PORTER-SCHEINMAN, Stephanie; (US).
MEINHOLD, Peter; (US).
DUNDON, Catherine, Asleson; (US).
ARISTIDOU, Aristos; (US).
URANO, Jun; (US).
LIES, Doug; (US).
PETERS, Matthew; (US).
DEY, Melissa; (US).
JANCAUSKAS, Justas; (US).
EVANS, Kent; (US).
KELLY, Julie; (US).
BERRY, Ruth; (US).
BASTIAN, Sabine; (US).
ARNOLD, Frances; (US)
Agent: VEITENHEIMER, Erich, E.; Cooley LLP 777 6th Street, N.W. Suite 1100 Washington, DC 20001 (US)
Priority Data:
61/304,069 12.02.2010 US
61/308,568 26.02.2010 US
61/282,641 10.03.2010 US
61/352,133 07.06.2010 US
61/411,885 09.11.2010 US
61/430,801 07.01.2011 US
Title (EN) YEAST MICROORGANISMS WITH REDUCED BY-PRODUCT ACCUMULATION FOR IMPROVED PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS
(FR) MICROORGANISMES DE TYPE LEVURE PRÉSENTANT UNE ACCUMULATION RÉDUITE DE SOUS-PRODUITS PERMETTANT UNE PRODUCTION AMÉLIORÉE DE CARBURANTS, PRODUITS CHIMIQUES ET ACIDES AMINÉS
Abstract: front page image
(EN)Recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites are provided. The recombinant microorganisms provided may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g.. acelolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived byproducts. Further, the recombinant microorganisms may be microorganisms of the Saccharomyces clade, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.
(FR)La présente invention concerne des microorganismes recombinés comprenant des voies de biosynthèse et des procédés d'utilisation desdits microorganismes recombinés pour produire divers métabolites bénéfiques. Dans divers aspects de l'invention, les microorganismes recombinés peuvent comprendre une ou plusieurs modifications permettant la réduction ou l'élimination des sous-produits dérivés de 3-céto-acide (par exemple acétolactate et 2-acéto-2-hydroxybutyrate) et/ou d'aldéhyde. Dans divers modes de réalisation décrits ici, les microorganismes recombinants peuvent être des microorganismes du clade Saccharomyces, des microorganismes de type levure Crabtree-négative, des microorganismes de type levure Crabtree-positive, des microorganismes de type levure post-WGD (whole genome duplication, duplication totale du génome), des microorganismes de type levure pré-WGD, et des microorganismes de type levure non fermentante.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)