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1. (WO2011142465) NOVEL PROTEIN AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/142465    International Application No.:    PCT/JP2011/061104
Publication Date: 17.11.2011 International Filing Date: 13.05.2011
IPC:
C12N 15/09 (2006.01), A61K 38/00 (2006.01), A61P 31/12 (2006.01), A61P 31/16 (2006.01), C07K 14/375 (2006.01), C07K 16/14 (2006.01), C12N 1/15 (2006.01), C12N 1/19 (2006.01), C12N 1/21 (2006.01), C12N 5/10 (2006.01), G01N 33/53 (2006.01)
Applicants: RIKEN [JP/JP]; 2-1, Hirosawa, Wako-shi, Saitama 3510198 (JP) (For All Designated States Except US).
OCHANOMIZU UNIVERSITY [JP/JP]; 2-1-1, Otsuka, Bunkyo-ku, Tokyo 1128610 (JP) (For All Designated States Except US).
YUKIGUNI MAITAKE CO., LTD. [JP/JP]; 89, Yokawa, Minamiuonuma-shi, Niigata 9496695 (JP) (For All Designated States Except US).
KOBAYASHI, Toshihide [JP/JP]; (JP) (For US Only).
KOBAYASHI, Tetsuyuki [JP/JP]; (JP) (For US Only).
NISHIBORI, Kozo [JP/JP]; (JP) (For US Only).
KURAHASHI, Atsushi [JP/JP]; (JP) (For US Only).
FUJIMORI, Fumihiro [JP/JP]; (JP) (For US Only)
Inventors: KOBAYASHI, Toshihide; (JP).
KOBAYASHI, Tetsuyuki; (JP).
NISHIBORI, Kozo; (JP).
KURAHASHI, Atsushi; (JP).
FUJIMORI, Fumihiro; (JP)
Agent: HARAKENZO WORLD PATENT & TRADEMARK; Daiwa Minamimorimachi Building, 2-6, Tenjinbashi 2-chome Kita, Kita-ku, Osaka-shi, Osaka 5300041 (JP)
Priority Data:
2010-112681 14.05.2010 JP
Title (EN) NOVEL PROTEIN AND USE THEREOF
(FR) NOUVELLE PROTÉINE ET UTILISATION DE CELLE-CI
(JA) 新規なタンパク質およびその利用
Abstract: front page image
(EN)Disclosed is a protein described by protein (A), (B), or (C): (A) protein described by the amino acid sequence of SEQ ID NO: 1; (B) protein described by an amino acid sequence in which one or more amino acids have been substituted, deleted, inserted, or added to the amino acid sequence of SEQ NO: 1 and having specific binding activity for a mixture of sphingolipids and cholesterol; and (C) protein described by an amino acid sequence that is 70% or greater identical to the amino acid sequence of SEQ ID NO: 1.
(FR)La présente invention concerne une protéine décrite par la protéine (A), (B) ou (C). Ainsi, la protéine (A) est décrite par la séquence d'acides aminés de SEQ ID NO: 1. La protéine (B) est décrite par une séquence d'acides aminés, d'une part dans laquelle un ou plusieurs acides aminés ont été substitués, supprimés, insérés, ou ajoutés par rapport à la séquence d'acides aminés de SEQ ID NO: 1, et d'autre part qui est dotée d'une activité de liaison spécifique pour un mélange de sphingolipides et de cholestérol. Enfin, la protéine (C) est décrite par une séquence d'acides aminés qui est à au moins 70% identique à la séquence d'acides aminés de SEQ ID NO: 1.
(JA) 下記(A)、(B)または(C)のタンパク質:(A)配列番号1のアミノ酸配列によって示される、タンパク質;(B)配列番号1のアミノ酸配列において、1若しくは複数個のアミノ酸が置換、欠失、挿入もしくは付加されているアミノ酸配列によって示されるタンパク質であって、スフィンゴ脂質とコレステロールとの混合体に対する特異的な結合活性を有する、タンパク質;(C)配列番号1のアミノ酸配列と70%以上の同一性を有するアミノ酸配列によって示される、タンパク質。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)