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1. (WO2011141923) IMPROVED SYNTHESIS OF OPTICALLY PURE (S) - 3-CYANO-5-METHYL-HEXANOIC ACID ALKYL ESTER, AN INTERMEDIATE OF (S)- PREGABALIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/141923    International Application No.:    PCT/IN2010/000440
Publication Date: 17.11.2011 International Filing Date: 28.06.2010
IPC:
C07C 253/30 (2006.01), C07C 67/08 (2006.01), C07C 67/343 (2006.01), C07C 231/02 (2006.01), C07C 253/20 (2006.01), C07C 51/363 (2006.01)
Applicants: LUPIN LIMITED [IN/IN]; 159, CST Road, Kalina Santacruz (East) Mumbai - 400 098 Maharashtra (IN) (For All Designated States Except US).
ROY, Bhairab, Nath [IN/IN]; (IN) (For US Only).
SINGH, Girij, Pal [IN/IN]; (IN) (For US Only).
LATHI, Piyush, Suresh [IN/IN]; (IN) (For US Only).
AGRAWAL, Manoj, Kunjabihari [IN/IN]; (IN) (For US Only).
PISE, Vijay, Sadashiv [IN/IN]; (IN) (For US Only)
Inventors: ROY, Bhairab, Nath; (IN).
SINGH, Girij, Pal; (IN).
LATHI, Piyush, Suresh; (IN).
AGRAWAL, Manoj, Kunjabihari; (IN).
PISE, Vijay, Sadashiv; (IN)
Agent: MAJUMDAR, Subhatosh; S. Majumdar & Co. 5, Harish Mukherjee Road Kolkata 700 025 (IN)
Priority Data:
536/KOL/2010 14.05.2010 IN
Title (EN) IMPROVED SYNTHESIS OF OPTICALLY PURE (S) - 3-CYANO-5-METHYL-HEXANOIC ACID ALKYL ESTER, AN INTERMEDIATE OF (S)- PREGABALIN
(FR) SYNTHÈSE AMÉLIORÉE D'UN ESTER ALKYLIQUE OPTIQUEMENT PUR DE L'ACIDE (S) - 3-CYANO-5-MÉTHYL-HEXANOÏQUE, INTERMÉDIAIRE DE LA (S)-PRÉGABALINE
Abstract: front page image
(EN)The present invention is directed towards synthesis of (S) - 3-cyano-5-methyl-hexanoic acid ethyl ester. A cost effective, eco-friendly process for preparation of enantiomerically pure (S)-3-cyano-5-methyl-hexanoic acid alkyl ester, intermediate of γ-amino acids, particularly (S)-pregabalin.
(FR)Cette invention concerne la synthèse d'un ester éthylique de l'acide (S)-3-cyano-5-méthyl-hexanoïque. Cette invention se rapporte en outre à un procédé écologique et peu onéreux pour préparer un ester alkylique énantiomériquement pur de l'acide (S)-3-cyano-5-méthyl-hexanoïque, un intermédiaire d'γ-amino-acides, en particulier de la (S)-prégabaline.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)