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1. (WO2011141474) NOVEL CCR2 RECEPTOR ANTAGONISTS, METHOD FOR PRODUCING THE SAME, AND USE THEREOF AS MEDICAMENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/141474    International Application No.:    PCT/EP2011/057545
Publication Date: 17.11.2011 International Filing Date: 10.05.2011
IPC:
C07D 401/14 (2006.01), C07D 405/14 (2006.01), C07D 413/14 (2006.01), C07D 487/04 (2006.01), C07D 491/10 (2006.01), C07D 495/04 (2006.01), C07D 471/04 (2006.01), A61K 31/4725 (2006.01), A61K 31/506 (2006.01), A61K 31/5377 (2006.01), A61P 37/00 (2006.01), A61P 9/00 (2006.01), A61P 25/00 (2006.01)
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Corporate Patents Binger Straße 173 55216 Ingelheim Am Rhein (DE) (For All Designated States Except US).
EBEL, Heiner [DE/DE]; (DE) (For US Only).
FRATTINI, Sara [IT/IT]; (DE) (For US Only).
GIOVANNINI, Riccardo [IT/IT]; (DE) (For US Only).
HOENKE, Christoph [DE/DE]; (DE) (For US Only).
MAZZAFERRO, Rocco [IT/IT]; (DE) (For US Only).
SCHEUERER, Stefan [DE/DE]; (DE) (For US Only)
Inventors: EBEL, Heiner; (DE).
FRATTINI, Sara; (DE).
GIOVANNINI, Riccardo; (DE).
HOENKE, Christoph; (DE).
MAZZAFERRO, Rocco; (DE).
SCHEUERER, Stefan; (DE)
Agent: HAMMANN, Heinz; Boehringer Ingelheim Gmbh Corporate Patents Binger Straße 173 55216 Ingelheim Am Rhein (DE)
Priority Data:
10162629.9 12.05.2010 EP
Title (EN) NOVEL CCR2 RECEPTOR ANTAGONISTS, METHOD FOR PRODUCING THE SAME, AND USE THEREOF AS MEDICAMENTS
(FR) NOUVEAUX ANTAGONISTES DES RÉCEPTEURS CCR2, PROCÉDÉ DE PRODUCTION ASSOCIÉ ET APPLICATION COMME MÉDICAMENTS
Abstract: front page image
(EN)The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) of formula (I) wherein HET is a group selected from among formulas (IIa) (IIb) (IIc) (IId) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD and pain diseases.
(FR)La présente invention concerne de nouveaux antagonistes de CCR2 (récepteurs aux chimiokines CC de type 2) de formule (I) où HET est un groupe choisi parmi les formules (IIa) (IIb) (IIc) (IId) et leur utilisation pour donner des médicaments permettant de traiter des états et des maladies, particulièrement des maladies pulmonaires comme l'asthme et la BPCO et les maladies impliquant de la douleur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)