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1. (WO2011140832) HEXAKETIDE COMPOUND AND MEDICINAL USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/140832    International Application No.:    PCT/CN2011/000848
Publication Date: 17.11.2011 International Filing Date: 16.05.2011
IPC:
C07D 295/03 (2006.01), C07C 275/20 (2006.01), C07C 335/10 (2006.01), A61K 31/17 (2006.01), A61K 31/5375 (2006.01), A61P 9/04 (2006.01), A61P 9/10 (2006.01), A61P 25/28 (2006.01), A61P 31/12 (2006.01)
Applicants: INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P. L. A. CHINA [CN/CN]; No. 27, Taiping Road, Haidian District Beijing 100850 (CN) (For All Designated States Except US).
LI, Song [CN/CN]; (CN) (For US Only).
ZHONG, Wu [CN/CN]; (CN) (For US Only).
LIU, Juan [CN/CN]; (CN) (For US Only).
WANG, Lili [CN/CN]; (CN) (For US Only).
HE, Kunlun [CN/CN]; (CN) (For US Only).
LONG, Long [CN/CN]; (CN) (For US Only).
XIAO, Junhai [CN/CN]; (CN) (For US Only).
ZHENG, Zhibing [CN/CN]; (CN) (For US Only).
LI, Wei [CN/CN]; (CN) (For US Only).
LI, Xin [CN/CN]; (CN) (For US Only).
HU, Guoliang [CN/CN]; (CN) (For US Only)
Inventors: LI, Song; (CN).
ZHONG, Wu; (CN).
LIU, Juan; (CN).
WANG, Lili; (CN).
HE, Kunlun; (CN).
LONG, Long; (CN).
XIAO, Junhai; (CN).
ZHENG, Zhibing; (CN).
LI, Wei; (CN).
LI, Xin; (CN).
HU, Guoliang; (CN)
Agent: CCPIT PATENT & TRADEMARK LAW OFFICE; 8th Floor, Vantone New World Plaza 2 Fuchengmenwai Street Beijing 100037 (CN)
Priority Data:
201010172482.0 14.05.2010 CN
Title (EN) HEXAKETIDE COMPOUND AND MEDICINAL USE THEREOF
(FR) COMPOSÉ D'HEXACÉTIDE ET SON UTILISATION MÉDICINALE
(ZH) 己烯酮类化合物及其医药用途
Abstract: front page image
(EN)The present invention discloses a compound of general formula (I), or isomer, pharmaceutically acceptable salt and solvate thereof, as well as composition, medicinal use, and preparative method thereof. Said composition further comprises pharmaceutically acceptable carriers, excipients or diluents. Said medicinal use is anti-apoptosis, or prophylaxis or treatment of apoptosis related diseases or symptoms, especially protection of myocardial cell, or prophylaxis or treatment of myocardial cell apoptosis related diseases or symptoms.
(FR)La présente invention concerne un composé de formule générale I, ou l'un de ses isomères, sels pharmaceutiquement acceptables et solvates, ainsi qu'une composition, une utilisation médicinale et un procédé de préparation dudit composé. Ladite composition comprend en outre des supports, excipients ou diluants pharmaceutiquement acceptables. Ladite utilisation médicinale est destinée à l'apoptose ou la prophylaxie ou le traitement de maladies ou de symptômes liés à l'apoptose, spécialement pour la protection des cellules myocardiques, la prophylaxie ou le traitement de maladies ou de symptômes liés à l'apoptose myocardique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)