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Machine translation
1. (WO2011140566) HPV DNA METHYLATION PATTERNS OF DIAGNOSTIC OR PROGNOSTIC SIGNIFICANCE IN CERVICAL CANCER SCREENING
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/140566    International Application No.:    PCT/US2011/035803
Publication Date: 10.11.2011 International Filing Date: 09.05.2011
IPC:
C12Q 1/68 (2006.01)
Applicants: YALE UNIVERSITY [US/US]; 2 Whitney Avenue New Haven, CT 06510 (US) (For All Designated States Except US).
BRANDSMA, Janet, L. [US/US]; (US) (For US Only).
LIZARDI, Paul, M. [US/US]; (US) (For US Only)
Inventors: BRANDSMA, Janet, L.; (US).
LIZARDI, Paul, M.; (US)
Agent: HODGES, Robert, A.; Pabst Patent Group LLP 1545 Peachtree Street, N.E. Suite 320 Atlanta, GA 30309 (US)
Priority Data:
61/332,376 07.05.2010 US
Title (EN) HPV DNA METHYLATION PATTERNS OF DIAGNOSTIC OR PROGNOSTIC SIGNIFICANCE IN CERVICAL CANCER SCREENING
(FR) MOTIFS DE MÉTHYLATION DE L'ADN DU HPV AYANT DES SIGNIFICATIONS DE DIAGNOSTIC OU DE PRONOSTIC DANS LE CRIBLAGE DU CANCER DU COL DE L'UTÉRUS
Abstract: front page image
(EN)Disclosed are methods, compositions, devices, and systems for assessing cancer potential, state, stage, risk of progression, prognosis, etc. of a subject based on determining the methylation state of human papillomavirus (HPV) in a sample from the subject. The cancers assessed generally can be cancer associated with or caused by HPV. For example, cervical cancer, vulvar cancer, penile cancer, anal cancer, and head and neck cancer can be associated with HPV. It has been discovered that certain patterns, profiles, and sets of methylation of HPV genomes are correlated with different cancer potential, state, stage, risk of progression, prognosis, etc.
(FR)L'invention concerne des procédés, des compositions, des dispositifs et des systèmes pour l'estimation du potentiel, de l'état, du stade, du risque de progression, du pronostic, etc., cancéreux d'un sujet sur la base de la détermination de l'état de méthylation du papillomavirus humain (HPV) dans un échantillon prélevé chez le sujet. Les cancers évalués peuvent être généralement des cancers associés au HPV ou provoqués par le HPV. Par exemple, le cancer du col de l'utérus, le cancer de la vulve, le cancer du pénis, le cancer anal et le cancer de la tête et du cou peuvent être associés au HPV. Il s'avère que certains motifs, profils et ensembles de méthylation de génomes du HPV sont mis en corrélation avec différents potentiels, états, stades, risques de progression, pronostics, etc., cancéreux.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)