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Machine translation
1. (WO2011140232) DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/140232    International Application No.:    PCT/US2011/035211
Publication Date: 10.11.2011 International Filing Date: 04.05.2011
IPC:
C07D 263/16 (2006.01), C07D 263/14 (2006.01), C07D 233/22 (2006.01), C07D 231/14 (2006.01), A61K 31/421 (2006.01), A61K 31/4164 (2006.01), A61P 3/10 (2006.01), A61P 31/12 (2006.01)
Applicants: SHIRE LLC [US/US]; 9200 Brookfield Court Florence, Kentucky 41042-2969 (US) (For All Designated States Except US).
MALECHA, James, W. [US/US]; (US) (For US Only)
Inventors: MALECHA, James, W.; (US)
Agent: BENNETT, Dennis, A.; Global Patent Group, LLC 1005 N. Warson Road, Suite 201 St. Louis, MO 63132 (US)
Priority Data:
61/331,138 04.05.2010 US
Title (EN) DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS
(FR) ANALOGUES DE DÉSAZADESFERROTHIOCINE ET DE POLYÉTHER DE DÉSAZADESFERROTHIOCINE UTILISÉS EN TANT QUE CHÉLATEURS MÉTALLIQUES
Abstract: front page image
(EN)Disclosed herein are new compounds of desazadesferrothiocin polyether (DADFT- PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
(FR)La présente invention concerne de nouveaux composés d'analogues de polyéther de désazadesferrothiocine (DADFT-PE), ainsi que des compositions pharmaceutiques en contenant et leur utilisation en tant que chélateurs métalliques en vue du traitement de maladies. L'invention concerne également des procédés de chélation du fer et d'autres métaux chez un sujet humain ou animal en vue du traitement d'une surcharge en métaux et de la toxicité associée à ladite surcharge.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)