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Machine translation
1. (WO2011140228) NUCLEAR RECEPTOR BINDING AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/140228    International Application No.:    PCT/US2011/035206
Publication Date: 10.11.2011 International Filing Date: 04.05.2011
IPC:
A01N 43/42 (2006.01), A61K 31/47 (2006.01)
Applicants: GTX, INC. [US/US]; 175 Toyota Plaza, 7th Floor Memphis, TN 38103 (US) (For All Designated States Except US).
NARAYANAN, Ramesh [US/US]; (US) (For US Only).
YEPURU, Muralimohan [IN/US]; (US) (For US Only).
DALTON, James, T. [US/US]; (US) (For US Only)
Inventors: NARAYANAN, Ramesh; (US).
YEPURU, Muralimohan; (US).
DALTON, James, T.; (US)
Agent: COHEN, Mark, S.; Pearl Cohen Zedek Latzer, LLP 1500 Broadway, 12th Floor New York, NY 10036 (US)
Priority Data:
12/773,515 04.05.2010 US
Title (EN) NUCLEAR RECEPTOR BINDING AGENTS
(FR) AGENTS DE LIAISONS AUX RÉCEPTEURS NUCLÉAIRES
Abstract: front page image
(EN)The present invention relates to methods for prevention and/or treatment of metabolic disorders, post-menopausal obesity and conditions associated with high fat diet consumption including, obesity, body weight gain, fat mass formation, bone mineral content reduction, white adipose tissue weight gain, increased cholesterol levels, increased leptin levels, insulin resistance, type II diabetes, increased blood glucose levels, inflammatory diseases, cardiovascular diseases, fatty liver condition (accumulation of fat in the liver), decreased uncoupling protein- 1 (UCP-1) levels and increased lipogenesis.
(FR)La présente invention concerne des procédés de prévention et/ou de traitement de troubles métaboliques, de l'obésité post-ménopause et d'états associés aux régimes alimentaires riches en graisses, notamment l'obésité, la prise de poids corporel, la formation de masse grasse, la réduction de la minéralisation osseuse, l'augmentation de la masse de tissus adipeux blancs, l'hypercholestérolémie, l'augmentation des taux de leptine, la résistance à l'insuline, le diabète de type II, l'augmentation de la glycémie, les maladies inflammatoires, les maladies cardiovasculaires, la stéatose hépatique (accumulation de graisse dans le foie), la diminution des taux de protéine découplante UCP-1 et l'augmentation de la lipogenèse.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)