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1. (WO2011140213) METHOD OF TREATING ALZHEIMER'S DISEASE USING PHARMACOLOGICAL CHAPERONES TO INCREASE PRESENILIN FUNCTION AND GAMMA-SECRETASE ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/140213    International Application No.:    PCT/US2011/035182
Publication Date: 10.11.2011 International Filing Date: 04.05.2011
IPC:
C07K 1/00 (2006.01)
Applicants: AMICUS THERAPEUTICS, INC. [US/US]; 6 Cedar Brook Drive Cranbury, NJ 08512 (US) (For All Designated States Except US).
WUSTMAN, Brandon [US/US]; (US) (For US Only).
STEVENS, Anthony [US/US]; (US) (For US Only)
Inventors: WUSTMAN, Brandon; (US).
STEVENS, Anthony; (US)
Agent: SCOLA, Daniel, A., Jr.; Hoffman & Baron, LLP 6900 Jericho Turnpike Syosset, NY 11791 (US)
Priority Data:
61/331,735 05.05.2010 US
Title (EN) METHOD OF TREATING ALZHEIMER'S DISEASE USING PHARMACOLOGICAL CHAPERONES TO INCREASE PRESENILIN FUNCTION AND GAMMA-SECRETASE ACTIVITY
(FR) MÉTHODE DE TRAITEMENT DE LA MALADIE D'ALZHEIMER PAR EMPLOI DE CHAPERONS PHARMACOLOGIQUES POUR AUGMENTER L'EFFET ET L'ACTIVITÉ GAMMA-SÉCRÉTASE DE LA PRÉSÉNILINE
Abstract: front page image
(EN)The present invention relates to a method for treating an individual having Alzheimer's Disease by using pharmacological chaperones that bind presenelin and thereby increase γ-secretase activity.
(FR)La présente invention concerne une méthode de traitement d'un individu atteint de la maladie d'Alzheimer par emploi de chaperons pharmacologiques se liant à la préséniline et augmentant ainsi l'activité γ-sécrétase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)