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1. (WO2011139993) SCREENING METHODS, COMPOSITIONS IDENTIFIED THEREBY, TOOLS USEFUL FOR THE IDENTIFICATION THEREOF, AND CELL POPULATIONS PRODUCED THEREBY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/139993    International Application No.:    PCT/US2011/034851
Publication Date: 10.11.2011 International Filing Date: 02.05.2011
IPC:
C12Q 1/02 (2006.01), C12N 5/00 (2006.01), G01N 33/48 (2006.01), G01N 33/15 (2006.01)
Applicants: MICROSTEM, INC. [US/US]; P.O. Box 181902 Coronado, CA 92178-1902 (US) (For All Designated States Except US).
ZHANG, Marie [US/US]; (US) (For US Only).
BINGHAM, Justin [US/US]; (US) (For US Only).
SEROBYAN, Naira [US/US]; (US) (For US Only)
Inventors: ZHANG, Marie; (US).
BINGHAM, Justin; (US).
SEROBYAN, Naira; (US)
Agent: REITER, Stephen, E.; Foley & Lardner LLP 3579 Valley Centre Drive, Suite 300 San Diego, CA 92130 (US)
Priority Data:
61/330,815 03.05.2010 US
61/446,971 25.02.2011 US
Title (EN) SCREENING METHODS, COMPOSITIONS IDENTIFIED THEREBY, TOOLS USEFUL FOR THE IDENTIFICATION THEREOF, AND CELL POPULATIONS PRODUCED THEREBY
(FR) PROCÉDÉS DE CRIBLAGE, COMPOSITIONS IDENTIFIÉES PAR CE PROCÉDÉ, OUTILS UTILES POUR LEUR IDENTIFICATION ET POPULATIONS CELLULAIRES AINSI PRODUITES
Abstract: front page image
(EN)In accordance with one aspect of the present invention, methods have been developed for identifying compositions which support the culture of defined cell populations. In accordance with another aspect of the present invention, methods have been developed for identifying compositions which promote differentiation of defined cell populations. In accordance with yet another aspect of the present invention, methods have been developed for identifying compositions which induce apoptosis of defined cell populations. In accordance with still another aspect of the present invention, methods have been developed for identifying compositions which promote cell senescence of defined cell populations. In accordance with still another aspect of the present invention, methods have been developed for identifying media which modulate the retardation of cell growth of defined cell subpopulation(s). In accordance with further aspects of the present invention, there are provided novel compositions identified by invention methods. Also provided are various uses of the novel compositions identified by invention methods, and novel cell populations produced employing same. In accordance with still another aspect of the present invention, methods have been developed for identifying compositions which support the culture of aberrant cell populations. In accordance with yet another aspect of the present invention, methods have been developed for identifying compositions which promote differentiation of aberrant cell populations. In accordance with still another aspect of the present invention, methods have been developed for identifying compositions which induce apoptosis of aberrant cell populations.
(FR)La présente invention concerne, selon un aspect, des procédés pour l'identification de compositions qui favorisent la culture de populations cellulaires définies. La présente invention concerne, selon un autre aspect, des procédés pour l'identification de compositions qui favorisent la différentiation de populations cellulaires définies. La présente invention concerne, selon un autre aspect, des procédés pour l'identification de compositions qui induisent l'apoptose de populations cellulaires définies. La présente invention concerne, selon un autre aspect, des procédés pour l'identification de compositions qui favorisent la sénescence cellulaire de populations cellulaires définies. La présente invention concerne, selon un autre aspect, des procédés pour l'identification de milieux qui modulent le retard de croissance cellulaire d'une ou de plusieurs sous-populations cellulaires définies. La présente invention concerne, selon d'autres aspects, de nouvelles compositions identifiées par les procédés de l'invention. L'invention concerne également diverses utilisations des nouvelles compositions identifiées par les procédés de l'invention, et de nouvelles populations cellulaires produites en les utilisant. La présente invention concerne, selon un aspect, des procédés pour l'identification de compositions qui favorisent la culture de populations cellulaires aberrantes. La présente invention concerne, selon un autre aspect, des procédés pour l'identification de compositions qui favorisent la différentiation de populations cellulaires aberrantes. La présente invention concerne, selon un autre aspect, des procédés pour l'identification de compositions qui induisent l'apoptose de populations cellulaires aberrantes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)