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1. (WO2011139911) LIPID FORMULATED SINGLE STRANDED RNA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/139911    International Application No.:    PCT/US2011/034648
Publication Date: 10.11.2011 International Filing Date: 29.04.2011
IPC:
C12N 15/88 (2006.01), C12N 15/13 (2006.01)
Applicants: ISIS PHARMACEUTICALS, INC. [US/US]; 2855 Gazelle Court Carlsbad, CA 92010 (US) (For All Designated States Except US).
ALNYLAM PHARMACEUTICALS, INC. [IN/US]; 300 Third Street Cambridge, MA 02142 (US) (For All Designated States Except US).
MANOHARAN, Muthiah [US/US]; (US) (For US Only).
ELBASHIR, Sadya, M. [DE/US]; (US) (For US Only).
RAJEEV, Kallanthottathil, G. [IN/US]; (US) (For US Only).
PRAKASH, Thazha, P. [IN/US]; (US) (For US Only).
LIMA, Walter, F. [US/US]; (US) (For US Only).
SWAYZE, Eric, E. [US/US]; (US) (For US Only)
Inventors: MANOHARAN, Muthiah; (US).
ELBASHIR, Sadya, M.; (US).
RAJEEV, Kallanthottathil, G.; (US).
PRAKASH, Thazha, P.; (US).
LIMA, Walter, F.; (US).
SWAYZE, Eric, E.; (US)
Agent: FORD, Clifford, E.; Isis Pharmaceuticals, Inc. 1896 Rutherford Rd. Carlsbad, CA 92008 (US)
Priority Data:
61/329,466 29.04.2010 US
Title (EN) LIPID FORMULATED SINGLE STRANDED RNA
(FR) ARN SIMPLE BRIN À FORMULATION LIPIDIQUE
Abstract: front page image
(EN)The present invention provides compositions comprising a nucleic acid lipid particle and an oligomeric compound and uses thereof. In certain embodiments, such compositions are useful as antisense compounds. Certain such antisense compounds are useful as RNase H antisense compounds or as RNAi compounds.
(FR)La présente invention concerne des compositions comportant une particule lipidique d'acide nucléique et un composé oligomérique ainsi que leurs utilisations. Selon certains modes de réalisation, de telles compositions sont utiles en tant que composés antisens. Certains de ces composés antisens sont utiles en tant que composés antisens de RNase H ou en tant que composés d'ARNi.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)