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Machine translation
1. (WO2011137459) DOSAGE FORMS OF ELINOGREL AND METHODS OF INJECTABLE ADMINISTRATION THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/137459    International Application No.:    PCT/US2011/034861
Publication Date: 03.11.2011 International Filing Date: 02.05.2011
IPC:
A61K 9/19 (2006.01), A61K 47/18 (2006.01), A61K 47/26 (2006.01), A61K 9/00 (2006.01), A61K 31/216 (2006.01), A61K 49/00 (2006.01), G01N 1/00 (2006.01)
Applicants: PORTOLA PHARMACEUTICALS, INC. [US/US]; 270 E. Grand Avenue, Suite 22 South San Francisco, California 94080 (US) (For All Designated States Except US).
NOVARTIS PHARMA AG [CH/CH]; Novartis Campus CH-4056 Basel (CH) (For All Designated States Except US).
LI, Hui [US/US]; (US) (For US Only).
WANG, Juan [US/US]; (US) (For US Only).
LAMBING, Joe [US/US]; (US) (For US Only).
TIEMESSEN, Harry [NL/DE]; (DE) (For US Only)
Inventors: LI, Hui; (US).
WANG, Juan; (US).
LAMBING, Joe; (US).
TIEMESSEN, Harry; (DE)
Agent: HOPKINS, Mark H.; Kilpatrick Townsend & Stockton LLP Two Embarcadero Center, Eighth Floor San Francisco, California 94111-3834 (US)
Priority Data:
61/329,725 30.04.2010 US
Title (EN) DOSAGE FORMS OF ELINOGREL AND METHODS OF INJECTABLE ADMINISTRATION THEREOF
(FR) FORMES GALÉNIQUES DE L'ÉLINOGREL ET LEURS MÉTHODES D'ADMINISTRATION INJECTABLES
Abstract: front page image
(EN)The present invention is concerned with a liquid delivery form of Elinogrel for the treatment of thrombosis which is notable for its improved dosage properties and stability. The dosage form is a liquid or a lyophilized form which is reconstituted for an injectable formulation comprising: a) at least about 3 mg/ml or up to about 15 mg/ml Elinogrel or a pharmaceutically acceptable salt thereof (post reconstitution or in liquid form), and b) at least one pharmaceutically acceptable excipient. Further aspects of the present invention concern the preparation and use of such a formulation.
(FR)La présente invention concerne une forme liquide d'administration de l'élinogrel pour le traitement de la thrombose qui est remarquable pour l'amélioration de ses propriétés galéniques et de sa stabilité. La forme galénique est une forme liquide ou lyophilisée qui est reconstituée pour une formulation injectable, comprenant : a) au moins environ 3 mg/ml ou jusqu'à environ 15 mg/ml d'élinogrel ou de l'un de ses sels pharmaceutiquement acceptables (après reconstitution ou sous forme liquide) et b) au moins un excipient pharmaceutiquement acceptable. D'autres aspects de la présente invention concernent la préparation et l'utilisation d'une telle formulation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)