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1. (WO2011137245) LYTIC-PEPTIDE-HER2/NEU (HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2) LIGAND CONJUGATES AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/137245    International Application No.:    PCT/US2011/034338
Publication Date: 03.11.2011 International Filing Date: 28.04.2011
IPC:
A61K 39/395 (2006.01), A61K 39/00 (2006.01), A61K 38/00 (2006.01), C07H 21/04 (2006.01), C12P 21/08 (2006.01)
Applicants: ESPERANCE PHARMACEUTICALS, INC. [US/US]; 340 E. Parker Blvd. Baton Rouge, LA 70803 (US) (For All Designated States Except US).
ALILA, Hector [US/US]; (US) (For US Only).
LEUSCHNER, Carola [DE/US]; (US) (For US Only).
JUBAN, Martha [US/US]; (US) (For US Only).
COULTER, Ann [US/US]; (US) (For US Only)
Inventors: ALILA, Hector; (US).
LEUSCHNER, Carola; (US).
JUBAN, Martha; (US).
COULTER, Ann; (US)
Agent: BEDGOOD, Robert, M.; PILLSBURY WINTHROP SHAW PITTMAN LLP P.O. Box 10500 McLean, VA 22101 (US)
Priority Data:
61/330,005 30.04.2010 US
61/362,603 08.07.2010 US
Title (EN) LYTIC-PEPTIDE-HER2/NEU (HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2) LIGAND CONJUGATES AND METHODS OF USE
(FR) CONJUGUÉS LIGAND HER2/NEU (RÉCEPTEUR 2 DU FACTEUR DE CROISSANCE ÉPIDERMIQUE HUMAIN)-PEPTIDE LYTIQUE ET MÉTHODES D'UTILISATION ASSOCIÉES
Abstract: front page image
(EN)Disclosed are conjugates comprising a ligand that binds to Her2/neu. The ligand comprises polypeptides including growth factors, hormones, antibodies, and antibody fragments. The disclosure also provides methods of using the conjugates that bind to Her2/neu for treating disorders associated with undesirable or aberrant cell proliferation including hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies that express Her2/neu.
(FR)L'invention concerne des conjugués se liant à Her2/neu, des méthodes d'utilisation des conjugués se liant à Her2/neu et des méthodes de traitement de la prolifération cellulaire indésirable ou aberrante ou des troubles hyperprolifératifs, tels que les tumeurs, les cancers, la néoplasie et les tumeurs malignes exprimant Her2/neu.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)