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1. (WO2011137243) FLUORESCENT FUSION POLYPEPTIDES AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/137243    International Application No.:    PCT/US2011/034330
Publication Date: 03.11.2011 International Filing Date: 28.04.2011
IPC:
C07K 19/00 (2006.01), C12N 15/62 (2006.01), G01N 33/52 (2006.01)
Applicants: STC.UNM [US/US]; 801 University Boulevard, S.E. Suite 101 Albuquerque, NM 87106 (US) (For All Designated States Except US).
MARKIV, Anatoliy [UA/GB]; (GB).
DURVASULA, Ravi [CA/US]; (US).
KANG, Angray, Singh [GB/GB]; (GB).
QUEEN MARY AND WESTFIELD COLLEGE, UNIVERSITY OF LONDON [--/GB]; Room E204 Queen's Building Queen Mary, University of London Mile End Road London E1 4NS (GB) (For All Designated States Except US)
Inventors: MARKIV, Anatoliy; (GB).
DURVASULA, Ravi; (US).
KANG, Angray, Singh; (GB)
Agent: GRAM, Christopher, D.; Mueting Raasch & Gebhardt, P.A. P.O. Box 581336 Minneaplois, MN 55458-1336 (US)
Priority Data:
61/343,627 30.04.2010 US
Title (EN) FLUORESCENT FUSION POLYPEPTIDES AND METHODS OF USE
(FR) POLYPEPTIDES DE FUSION FLUORESCENTS ET PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)Embodiments of the present invention provide for the facile generation of a stable recombinant fusion polypeptides with intrinsic fluorescent properties. The recombinant antibodies may be suitable for qualitative and/or quantitative immunofluorescence analysis. Generally, the fluorescent polypeptides include a fluorescent domain comprising a C-terminus and an N-terminus; a first antibody domain covalently linked to the C-terminus; and a second antibody domain covalently linked to the N-terminus.
(FR)Les modes de réalisation de la présente invention permettent la génération facile de polypeptides de fusion recombinés stables ayant des propriétés fluorescentes intrinsèques. Les anticorps recombinés peuvent se prêter à une analyse par immunofluorescence qualitative et/ou quantitative. De manière générale, les polypeptides fluorescents selon l'invention comprennent un domaine fluorescent contenant une extrémité C-terminale et une extrémité N-terminale ; un premier domaine d'anticorps lié par covalence à l'extrémité C-terminale ; et un second domaine d'anticorps lié par covalence à l'extrémité N-terminale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)