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1. (WO2011136459) NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/136459    International Application No.:    PCT/KR2010/009096
Publication Date: 03.11.2011 International Filing Date: 20.12.2010
IPC:
C07D 211/38 (2006.01)
Applicants: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY [KR/KR]; Gwangju Institute of Science and Technology 261 Cheomdan-gwagiro(1 Oryong-dong), Buk-gu Gwangju 500-712 (KR) (For All Designated States Except US).
KIM, Yong-Chul [KR/KR]; (KR) (For US Only).
JUNG, Kwan-Young [KR/KR]; (KR) (For US Only).
CHO, Joong Heui [KR/KR]; (KR) (For US Only)
Inventors: KIM, Yong-Chul; (KR).
JUNG, Kwan-Young; (KR).
CHO, Joong Heui; (KR)
Agent: YANG, Boo-Hyun; Suite 301 Chungdong Building 1659-2 Inhundong, Gwanak-gu Seoul 151-832 (KR)
Priority Data:
10-2010-0038535 26.04.2010 KR
Title (EN) NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME
(FR) NOUVEAU COMPOSÉ À BASE D'ACIDE PYRIDINECARBOXYLIQUE UTILISÉ EN TANT QU'ANTAGONISTE DE RÉCEPTEUR P2X1 ET P2X3, PROCÉDÉ DE PRODUCTION POUR CELUI-CI ET COMPOSITION COMPRENANT CELUI-CI
(KO) P2X1 및 P2X3 수용체 길항제로 사용되는 신규한 피리딘 카르복실산계 화합물, 이의 제조방법 및 이를 포함하는 조성물
Abstract: front page image
(EN)Provided are a novel pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same. The compound according to the present invention is a powerful antagonist of P2X1 and P2X3 receptors, and hence can be used as a drug for treating or preventing diseases involving neurological pain or chronic inflammatory diseases which are diseases caused by P2X1 and P2X3 receptor activity.
(FR)La présente invention concerne un nouveau composé à base d'acide pyridinecarboxylique utilisé en tant qu'antagoniste de récepteur P2X1 et P2X3, un procédé de production pour celui-ci et une composition comprenant celui-ci. Le composé selon la présente invention est un antagoniste puissant des récepteurs P2X1 et P2X3, et par conséquent, peut être utilisé en tant que médicament pour traiter ou prévenir des maladies impliquant une douleur neurologique ou des maladies inflammatoires chroniques qui sont des maladies causées par l'activité des récepteurs P2X1 et P2X3.
(KO)본 발명은 P2X1 및 P2X3 수용체 길항제로 유용한 신규한 피리딘 카르복실산 계 화합물, 이의 제조방법 및 이를 포함하는 조성물을 제공한다. 본 발명에 따른 화합물은 P2X1 및 P2X3 수용체를 강력하게 길항하므로, P2X1 및 P2X3 수용체 활성에 기인한 질환인 만성염증 질환 또는 신경성 통증 질환의 치료 및 예방을 위한 약제로 이용 가능하다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)