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1. (WO2011136264) [5,6] HETEROCYCLIC COMPOUND
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/136264    International Application No.:    PCT/JP2011/060241
Publication Date: 03.11.2011 International Filing Date: 27.04.2011
C07D 235/06 (2006.01), A61K 31/4184 (2006.01), A61K 31/4188 (2006.01), A61K 31/427 (2006.01), A61K 31/437 (2006.01), A61K 31/4439 (2006.01), A61K 31/444 (2006.01), A61K 31/454 (2006.01), A61K 31/4545 (2006.01), A61K 31/496 (2006.01), A61K 31/506 (2006.01), A61K 31/5377 (2006.01), A61P 5/18 (2006.01), A61P 19/08 (2006.01), A61P 19/10 (2006.01), C07D 401/04 (2006.01), C07D 403/04 (2006.01), C07D 405/12 (2006.01), C07D 405/14 (2006.01), C07D 417/04 (2006.01), C07D 471/04 (2006.01), C07D 491/056 (2006.01)
Applicants: DAIICHI SANKYO COMPANY,LIMITED [JP/JP]; 3-5-1,Nihonbashi Honcho,Chuo-ku, Tokyo 1038426 (JP) (For All Designated States Except US).
AOKI, Kazumasa; (For US Only).
MATSUI, Satoshi; (For US Only).
YOSHIKAWA, Kenji; (For US Only).
SHIMIZU,Hiroki; (For US Only).
SASAKI, Junko; (For US Only).
NAKAJIMA, Katsuyoshi; (For US Only).
KANNO, Osamu; (For US Only).
OIZUMI, Kiyoshi; (For US Only)
Inventors: AOKI, Kazumasa; .
MATSUI, Satoshi; .
SHIMIZU,Hiroki; .
SASAKI, Junko; .
NAKAJIMA, Katsuyoshi; .
KANNO, Osamu; .
OIZUMI, Kiyoshi;
Agent: ISHIBASHI Koki; c/o DAIICHI SANKYO COMPANY, LIMITED, 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 1400005 (JP)
Priority Data:
2010-103349 28.04.2010 JP
(JA) [5,6]複素環化合物
Abstract: front page image
(EN)Provided is a novel low-molecular-weight compound having ossification-promoting activity. The novel low-molecular-weight compound is a compound represented by general formula (I) (I) (where R1 and R2 are hydrogen atoms, and the like; R3 is a hydrogen atom, and the like; X, Y, and Z are nitrogen atoms, and the like; A is a phenylene group, and the like; n is 1 or 2, and the like; and V and W are oxygen atoms, and the like), or a pharmaceutically acceptable salt thereof.
(FR)La présente invention concerne un nouveau composé de faible masse moléculaire présentant une activité favorisant l'ossification. Ce nouveau composé de faible masse moléculaire est un composé représenté par la formule générale (I) (I) (dans laquelle R1 et R2 sont des atomes d'hydrogène, et analogues ; R3 est un atome d'hydrogène, et analogues ; X, Y, et Z sont des atomes d'azote, et analogues ; A est un groupe phénylène, et analogues ; n vaut 1 ou 2, et analogues ; et V et W sont des atomes d'oxygène, et analogues), ou un de ses sels pharmaceutiquement acceptables.
(JA)本発明の課題は、骨形成促進作用を有する新規な低分子化合物を提供することである。 その解決手段は、一般式(I)を有する化合物又はその薬理上許容される塩である。 [式中、R及びR:水素原子等;R:水素原子等;X、Y、Z:窒素原子等;A:フェニレン基等;n:1又は2等;V及びW:酸素原子等]
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)