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Machine translation
1. (WO2011134056) METHODS AND USES OF TIE2 BINDING AND/OR ACTIVATING AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/134056    International Application No.:    PCT/CA2011/000473
Publication Date: 03.11.2011 International Filing Date: 28.04.2011
IPC:
A61K 38/17 (2006.01), A61K 39/395 (2006.01), A61K 47/48 (2006.01), A61P 11/00 (2006.01), A61P 11/06 (2006.01), A61P 37/08 (2006.01)
Applicants: SUNNYBROOK HEALTH SCIENCES CENTRE [CA/CA]; S-133, 2075 Bayview Avenue Toronto, Ontario M4N 3M5 (CA) (For All Designated States Except US).
VAN SLYKE, Paul [CA/CA]; (CA) (For US Only).
DUMONT, Daniel [CA/CA]; (CA) (For US Only)
Inventors: VAN SLYKE, Paul; (CA).
DUMONT, Daniel; (CA)
Agent: BERESKIN & PARR LLP/S.E.N.C.R.L., S.R.L.; 40 King Street West 40th Floor Toronto, Ontario M5H 3Y2 (CA)
Priority Data:
61/328,932 28.04.2010 US
Title (EN) METHODS AND USES OF TIE2 BINDING AND/OR ACTIVATING AGENTS
(FR) PROCÉDÉS ET UTILISATIONS D'AGENTS DE LIAISON À TIE2 ET/OU D'AGENTS D'ACTIVATION DE TIE2
Abstract: front page image
(EN)The present disclosure provides methods and uses of Tie2 binding and/or activating agents. In particular, the present disclosure provides methods and uses for inhibiting the expansion of colony forming unit-granulocytes, reducing eosinophils and/or basophils, for treating allergic disease or response or eosinophil/basophil associated condition and for reducing inflammatory cytokine and/or chemokine levels.
(FR)La présente invention porte sur des procédés et sur des utilisations d'agents de liaison à Tie2 et/ou d'agents d'activation de Tie2. En particulier, la présente invention porte sur des procédés et sur des utilisations pour l'inhibition de l'expansion d'unités de formation de colonies de granulocytes, la réduction du nombre d'éosinophiles et/ou de basophiles, pour le traitement de maladies ou de réponses allergiques ou d'états associés aux éosinophiles/basophiles et pour la réduction des taux de cytokines et/ou de chimiokines inflammatoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)