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1. (WO2011134019) NOVEL BIPHENYL SARTANS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/134019    International Application No.:    PCT/AU2011/000495
Publication Date: 03.11.2011 International Filing Date: 29.04.2011
IPC:
C07D 487/04 (2006.01), C07D 403/10 (2006.01), C07D 403/12 (2006.01), C07D 487/10 (2006.01), C07D 403/04 (2006.01), C07D 403/14 (2006.01), C07D 495/04 (2006.01), C07D 403/06 (2006.01), C07D 409/14 (2006.01), C07D 471/04 (2006.01), A61K 31/513 (2006.01), A61K 31/4188 (2006.01), A61P 25/28 (2006.01), A61K 31/41 (2006.01), A61K 31/437 (2006.01), A61P 39/06 (2006.01), A61K 31/4178 (2006.01), A61K 31/454 (2006.01), A61K 31/4184 (2006.01), A61P 9/12 (2006.01)
Applicants: THE UNIVERSITY OF MELBOURNE [AU/AU]; Grattan Street Parkville, Victoria 3052 (AU) (For All Designated States Except US).
SCHIESSER, Carl Herbert [AU/AU]; (AU) (For US Only).
TAN, Phei Hsin [MY/AU]; (AU) (For US Only).
ZIOGAS, James [AU/AU]; (AU) (For US Only).
JANI, Nitya Vipin [GB/AU]; (AU) (For US Only).
WRIGHT, Christine Eva [AU/AU]; (AU) (For US Only).
TAYLOR, Michelle Keily [GB/AU]; (AU) (For US Only)
Inventors: SCHIESSER, Carl Herbert; (AU).
TAN, Phei Hsin; (AU).
ZIOGAS, James; (AU).
JANI, Nitya Vipin; (AU).
WRIGHT, Christine Eva; (AU).
TAYLOR, Michelle Keily; (AU)
Agent: LUCAS, Mathew A; DAVIES COLLISON CAVE 1 Nicholson Street Melbourne, Victoria 3000 (AU)
Priority Data:
2010901858 30.04.2010 AU
Title (EN) NOVEL BIPHENYL SARTANS
(FR) NOUVEAUX BIPHÉNYLSARTANS
Abstract: front page image
(EN)The present invention relates to compounds and compositions useful in modulating the renin-angiotensin system (RAS) in cells, and in particular to compounds which, inter alia, act as angiotensin II antagonists by binding to angiotensin II receptors. The invention also relates to the use of these compounds and compositions in the treatment of conditions responsive to angiotensin II antagonists such as hypertension, edema, renal failure, benign prostatic hypertrophy glaucoma, atherosclerosis, diabetes, Alzheimer's disease and congestive heart failure.
(FR)La présente invention concerne des composés et des compositions pouvant être employés dans la modulation du système rénine-angiotensine (SRA) dans les cellules, et en particulier des composés qui peuvent entre autres agir au titre d'antagonistes de l'angiotensine II en se liant aux récepteurs de l'angiotensine II. La présente invention concerne également l'emploi desdits composés et compositions dans le traitement des états pathologiques sensibles aux antagonistes de l'angiotensine II tels qu'hypertension, œdème, insuffisance rénale, hypertrophie bénigne de la prostate, glaucome, athérosclérose, diabète, maladie d'Alzheimer et insuffisance cardiaque congestive.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)