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1. (WO2011131746) HETERODIMERIC ANTIBODY FC-CONTAINING PROTEINS AND METHODS FOR PRODUCTION THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2011/131746 International Application No.: PCT/EP2011/056388
Publication Date: 27.10.2011 International Filing Date: 20.04.2011
IPC:
C07K 16/28 (2006.01) ,C07K 16/46 (2006.01) ,C07K 16/10 (2006.01) ,C07K 16/32 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46
Hybrid immunoglobulins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08
against material from viruses
10
from RNA viruses
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
32
against translation products from oncogenes
Applicants:
LABRIJN, Aran, Frank [NL/NL]; NL (UsOnly)
MEESTERS, Joyce [NL/NL]; NL (UsOnly)
BREMER, Ewald van den [NL/NL]; NL (UsOnly)
NEIJSSEN, Joost, J. [NL/NL]; NL (UsOnly)
BERKEL, Patrick van [NL/NL]; NL (UsOnly)
GOEIJ, Bart de [NL/NL]; NL (UsOnly)
VINK, Tom [NL/NL]; NL (UsOnly)
VAN DE WINKEL, Jan [NL/NL]; NL (UsOnly)
SCHUURMAN, Janine [NL/NL]; NL (UsOnly)
PARREN, Paul [NL/NL]; NL (UsOnly)
GENMAB A/S [DK/DK]; P.O. Box 9068 Bredgade 34 DK-1260 Copenhagen K, DK (AllExceptUS)
Inventors:
LABRIJN, Aran, Frank; NL
MEESTERS, Joyce; NL
BREMER, Ewald van den; NL
NEIJSSEN, Joost, J.; NL
BERKEL, Patrick van; NL
GOEIJ, Bart de; NL
VINK, Tom; NL
VAN DE WINKEL, Jan; NL
SCHUURMAN, Janine; NL
PARREN, Paul; NL
Priority Data:
61/326,08220.04.2010US
PA 2010 0033020.04.2010DK
PA 2010 0106624.11.2010DK
Title (EN) HETERODIMERIC ANTIBODY FC-CONTAINING PROTEINS AND METHODS FOR PRODUCTION THEREOF
(FR) PROTÉINES CONTENANT DES ANTICORPS FC HÉTÉRODIMÈRES ET LEURS PROCÉDÉS DE PRODUCTION
Abstract:
(EN) Heterodimeric antibody-Fc-containing proteins, such as bispecific antibodies, and novel methods for producing such proteins.
(FR) La présente invention a pour objet de nouvelles protéines contenant des anticorps Fc hétérodimères, tels que des anticorps bispécifiques, et de nouveaux procédés de production de telles protéines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)