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1. WO2011127240 - METHODS OF USING DIACEREIN AS AN ADJUNCTIVE THERAPY FOR DIABETES

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Publication Number WO/2011/127240
Publication Date 13.10.2011
International Application No. PCT/US2011/031517
International Filing Date 07.04.2011
IPC
A01N 35/00 2006.1
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
35Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
A61K 31/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
CPC
A61K 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
A61K 31/145
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
145having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
A61K 31/155
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
A61K 31/225
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
225Polycarboxylic acids
A61K 31/277
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
275Nitriles; Isonitriles
277having a ring, e.g. verapamil
A61K 31/426
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
425Thiazoles
4261,3-Thiazoles
Applicants
  • TWI BIOTECHNOLOGY, INC. (AllExceptUS)
  • KU, Mannching, Sherry [US]/[US] (UsOnly)
  • GAO, Danchen [US]/[US] (UsOnly)
  • LU, Wei-shu (UsOnly)
  • CHEN, Chih-ming (UsOnly)
  • LIN, I-Yin (UsOnly)
Inventors
  • KU, Mannching, Sherry
  • GAO, Danchen
  • LU, Wei-shu
  • CHEN, Chih-ming
  • LIN, I-Yin
Agents
  • KATZ, Martin, L.
Priority Data
61/321,93108.04.2010US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF USING DIACEREIN AS AN ADJUNCTIVE THERAPY FOR DIABETES
(FR) MÉTHODES D'UTILISATION DE LA DIACÉRÉINE COMME TRAITEMENT D'APPOINT DU DIABÈTE
Abstract
(EN) The present invention provides methods of treating type II diabetes using combinations of diacerein or its derivatives with other antidiabetic agents. The methods may also allow improving glycemic control of type II diabetes patients and/or reducing side effects and/or cardiovascular risks of antidiabetic agents.
(FR) Méthodes de traitement du diabète de type II au moyen de combinaisons de diacéréine ou de ses dérivés et d'autres agents antidiabétiques. Ces méthodes peuvent également permettre d'améliorer la régulation de la glycémie chez des patients atteints d'un diabète de type II et/ou de réduire les effets secondaires et/ou les risques cardiovasculaires afférents aux agents antidiabétiques.
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