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1. WO2011126931 - RESPONSIVENESS TESTING OF A PATIENT HAVING BRAIN STATE CHANGES

Publication Number WO/2011/126931
Publication Date 13.10.2011
International Application No. PCT/US2011/030866
International Filing Date 01.04.2011
IPC
A61B 5/0476 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
04Measuring bioelectric signals of the body or parts thereof
0476Electroencephalography
A61B 5/16 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
16Devices for psychotechnics; Testing reaction times
CPC
A61B 5/165
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
16Devices for psychotechnics
165Evaluating the state of mind, e.g. depression, anxiety
A61B 5/369
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
316Modalities, i.e. specific diagnostic methods
369Electroencephalography [EEG]
A61B 5/4035
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
40Detecting, measuring or recording for evaluating the nervous system
4029for evaluating the peripheral nervous systems
4035Evaluating the autonomic nervous system
A61B 5/4094
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
40Detecting, measuring or recording for evaluating the nervous system
4076Diagnosing or monitoring particular conditions of the nervous system
4094Diagnosing or monitoring seizure diseases, e.g. epilepsy
A61B 5/7264
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
72Signal processing specially adapted for physiological signals or for diagnostic purposes
7235Details of waveform analysis
7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
A61B 5/7275
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
72Signal processing specially adapted for physiological signals or for diagnostic purposes
7271Specific aspects of physiological measurement analysis
7275Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
Applicants
  • FLINT HILLS SCIENTIFIC, LLC [US]/[US] (AllExceptUS)
  • OSORIO, Ivan [US]/[US] (UsOnly)
Inventors
  • OSORIO, Ivan
Agents
  • SCOTT, Timothy, L.
Priority Data
12/756,06507.04.2010US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) RESPONSIVENESS TESTING OF A PATIENT HAVING BRAIN STATE CHANGES
(FR) TEST DE RÉACTIVITÉ D'UN PATIENT PRÉSENTANT DES CHANGEMENTS D'ÉTAT CÉRÉBRAL
Abstract
(EN) A method of determining a responsiveness of a patient having brain state changes, comprising receiving an indication of a triggering event; administering to the patient, in response to the indication, a test of responsiveness; determining, based upon a result of the test, at least one responsiveness parameter selected from the group consisting of (i) a time of occurrence of a change in the patient's responsiveness, (ii) a duration of a change in the patient's responsiveness; (iii) a magnitude of a change in the patient's responsiveness, (iv) a time interval from the indication of event occurrence to a change in the patient's responsiveness, (v) a type of change in the patient's responsiveness, (vi) an estimation of a seizure severity; (vii) a classification of a seizure into clinical or subclinical; (viii) a classification of a clinical seizure into simple partial, complex partial, or generalized; (ix) an assessment of efficacy of a therapy for the patient's medical condition; (x) an assessment of the state of the disease and formulation of a prognosis for the patient; (xi) an estimation of a risk of injury or death for the patient; and (xii) two or more thereof. A medical device system capable of implementing the method.
(FR) L'invention concerne un procédé de détermination d'une réactivité d'un patient présentant des changements d'état cérébral comprenant la réception d'une indication d'un événement déclencheur ; l'administration au patient, en réponse à l'indication, d'un test de réactivité ; la détermination, basée sur un résultat du test, d'au moins un paramètre de réactivité choisi dans le groupe consistant en (i) un temps d'apparition d'un changement dans la réactivité du patient, (ii) une durée d'un changement dans la réactivité du patient ; (iii) une amplitude d'un changement dans la réactivité du patient, (iv) un intervalle de temps entre l'indication de l'apparition d'un événement et un changement dans la réactivité du patient, (v) un type de changement dans la réactivité du patient, (vi) une estimation de la sévérité de la crise d'épilepsie ; (vii) une classification d'une crise d'épilepsie comme clinique ou sous-clinique ; (viii) une classification d'une crise d'épilepsie clinique comme partielle simple, partielle complexe ou généralisée ; (ix) une estimation de l'efficacité d'une thérapie pour l'état médical du patient ; (x) une estimation de l'état de la maladie et la formulation d'un pronostic pour le patient ; (xi) une estimation d'un risque de lésion ou de mort pour le patient ; et (xii) deux ou plusieurs de ceux-ci. L'invention concerne également un système de dispositif médical capable de mettre en œuvre le procédé.
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