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1. WO2011119960 - SYSTEM AND METHOD FOR FRAMELESS STEREOTACTIC RADIOSURGERY OF ARTERIOVENOUS MALFORMATIONS

Publication Number WO/2011/119960
Publication Date 29.09.2011
International Application No. PCT/US2011/029997
International Filing Date 25.03.2011
IPC
A61B 5/05 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
05Measuring for diagnosis by means of electric currents or magnetic fields
CPC
A61B 2090/101
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
10for stereotaxic surgery, e.g. frame-based stereotaxis
101for stereotaxic radiosurgery
A61B 2090/363
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
36Image-producing devices or illumination devices not otherwise provided for
363Use of fiducial points
A61B 2090/364
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
36Image-producing devices or illumination devices not otherwise provided for
364Correlation of different images or relation of image positions in respect to the body
A61B 2090/376
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
36Image-producing devices or illumination devices not otherwise provided for
37Surgical systems with images on a monitor during operation
376using X-rays, e.g. fluoroscopy
A61B 2090/3762
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
36Image-producing devices or illumination devices not otherwise provided for
37Surgical systems with images on a monitor during operation
376using X-rays, e.g. fluoroscopy
3762using computed tomography systems [CT]
A61B 2090/3966
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
90Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
39Markers, e.g. radio-opaque or breast lesions markers
3966Radiopaque markers visible in an X-ray image
Applicants
  • BETH ISRAEL DEACONESS MEDICAL CENTER [US]/[US] (AllExceptUS)
  • LU, Xing-Qi [US]/[US] (UsOnly)
  • MATHIOWITZ, George [US]/[US] (UsOnly)
Inventors
  • LU, Xing-Qi
  • MATHIOWITZ, George
Agents
  • STONE, Jonathan, D.
Priority Data
61/317,59025.03.2010US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) SYSTEM AND METHOD FOR FRAMELESS STEREOTACTIC RADIOSURGERY OF ARTERIOVENOUS MALFORMATIONS
(FR) SYSTÈME ET MÉTHODE DE RADIOCHIRURGIE STÉRÉOTAXIQUE SANS CADRE DES MALFORMATIONS ARTÉRIOVEINEUSES
Abstract
(EN) A system and method for frameless stereotactic radiosurgery of arteriovenous malformations ("AVMs") are provided. In particular, digital subtraction angiography ("DSA") is utilized to obtain two-dimensional angiograms depicting the location and extent of a nidus of an AVM in a patient. Without using an invasive stereotactic frame affixed to the patient, the location and extent of the nidus is transformed into three- dimensional coordinates that can be registered with an x-ray computed tomography ("CT"] image volume of the patient. The determination of the nidus volume-of-interest ("VOI") from the two-dimensional angiograms is aided by the acquisition of radiograph images of a localizer box. These localizer radiographs are obtained with the same x-ray imaging system using same setup used to obtain the angiograms of the patient.
(FR) Système et méthode de radiochirurgie stéréotaxique sans cadre des malformations artérioveineuses ( » MAV »). On utilise, en particulier, une angiographie numérisée en soustraction ( » ANS ») pour obtenir des angiographies bidimensionnelles montrant la localisation et l'étendue d'un nidus de MAV chez un patient. Sans utiliser de cadre stéréotaxique invasif fixé au patient, la localisation et l'étendue du nidus sont transformées en coordonnées tridimensionnelles qui peuvent être recalées avec des images volumétriques du patient obtenues par tomodensitométrie X (CT). La détermination du volume d'intérêt ( » VOI ») du nidus à partir d'angiographies bidimensionnelles est facilitée par l'acquisition des images radiographiques d'un boîtier localisateur. Ces radiographies de localisateur sont obtenues avec le même système d'imagerie par rayons X et la même configuration que ceux utilisés pour obtenir les angiographies du patient.
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