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1. (WO2011117851) TRANSDERMAL ADMINISTRATION OF PEPTIDES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2011/117851 International Application No.: PCT/IE2011/000019
Publication Date: 29.09.2011 International Filing Date: 23.03.2011
IPC:
A61K 38/04 (2006.01) ,A61K 47/12 (2006.01) ,A61K 9/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
12
Carboxylic acids; Salts or anhydrides thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
Applicants:
IPSEN MANUFACTURING IRELAND LIMITED [IE/IE]; Blanchardstown Industrial Park Blanchardstown Dublin 15, IE (AllExceptUS)
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN [IE/IE]; College Green Dublin 2, IE (AllExceptUS)
DEASY, Patrick Bernard [IE/IE]; IE (UsOnly)
LOUGHMAN, Thomas Ciarán [IE/IE]; IE (UsOnly)
Inventors:
DEASY, Patrick Bernard; IE
LOUGHMAN, Thomas Ciarán; IE
Agent:
ANNE RYAN & CO.; 60 Northumberland Road Ballsbridge Dublin 4, IE
Priority Data:
2010/017425.03.2010IE
Title (EN) TRANSDERMAL ADMINISTRATION OF PEPTIDES
(FR) ADMINISTRATION TRANSDERMIQUE DE PEPTIDES
Abstract:
(EN) The present invention relates to a method of increasing the bioavailability of a peptide. The method includes altering the lipophilicity of a peptide by the creation of fatty acid peptide salts of the peptide. The fatty acid peptide salts exhibit increased transdermal and transmucosal permeability.
(FR) La présente invention concerne un procédé d'augmentation de la biodisponibilité d'un peptide. Le procédé comprend la modification de l'hydrophobicité d'un peptide par la création de sels acide gras-peptide du peptide. Les sels acide gras-peptide présentent une perméabilité transdermique et transmuqueuse augmentée.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
UAa201212235EP2550005US20130085105JP2013523629CN102883735CA2792470
RU2012145278MX2012010343KR1020130062275BR112012022377AU2011231173IN9130/DELNP/2012