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118. (WO2011107437) MICROVESICLES (MVS) DERIVED FROM ADULT STEM CELLS FOR USE IN THE THERAPEUTIC TREATMENT OF A TUMOR DISEASE

Pub. No.:    WO/2011/107437    International Application No.:    PCT/EP2011/052945
Publication Date: Sat Sep 10 01:59:59 CEST 2011 International Filing Date: Tue Mar 01 00:59:59 CET 2011
IPC: A61K 35/12
A61P 35/00
Applicants: FRESENIUS MEDICAL CARE DEUTSCHLAND G.M.B.H.
BRUNO, Stefania
HERRERA SANCHEZ, Maria Beatriz
FONSATO, Valentina
CAMUSSI, Giovanni
TETTA, Ciro
Inventors: BRUNO, Stefania
HERRERA SANCHEZ, Maria Beatriz
FONSATO, Valentina
CAMUSSI, Giovanni
TETTA, Ciro
Title: MICROVESICLES (MVS) DERIVED FROM ADULT STEM CELLS FOR USE IN THE THERAPEUTIC TREATMENT OF A TUMOR DISEASE
Abstract:
The invention is in the field of therapeutic treatment of tumours. The inventors have found that microvesicles derived from adult stem cells exert a remarkable anti-tumour effect when administered to a patient affected by a tumour disease. Preferred microvesicles are derived from a bone marrow-mesenchymal stem cell, a glomerular mesenchymal stem cell or a non-oval liver stem cell.