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1. WO2011093185 - METHOD FOR MANUFACTURING A PYRIPYROPENE

Publication Number WO/2011/093185
Publication Date 04.08.2011
International Application No. PCT/JP2011/050851
International Filing Date 19.01.2011
IPC
C12P 17/18 2006.1
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PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
17Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms
18containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
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NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
14Fungi ; Culture media therefor
15modified by introduction of foreign genetic material
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1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
21modified by introduction of foreign genetic material
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5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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C12N 15/09 2006.1
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09Recombinant DNA-technology
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63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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0004Oxidoreductases (1.)
0071acting on paired donors with incorporation of molecular oxygen (1.14)
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1029transferring groups other than amino-acyl groups (2.3.1)
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88Lyases (4.)
Applicants
  • Meiji Seikaファルマ株式会社 MEIJI SEIKA PHARMA CO., LTD. [JP]/[JP] (AllExceptUS)
  • 安西 弘行 ANZAI Hiroyuki [JP]/[JP] (UsOnly)
  • 山本 憲太朗 YAMAMOTO Kentaro [JP]/[JP] (UsOnly)
  • 尾山 和彦 OYAMA Kazuhiko [JP]/[JP] (UsOnly)
  • 土田 麻里子 TSUCHIDA Mariko [JP]/[JP] (UsOnly)
  • 後藤 公彦 GOTO Kimihiko [JP]/[JP] (UsOnly)
  • 三冨 正明 MITOMI Masaaki [JP]/[JP] (UsOnly)
Inventors
  • 安西 弘行 ANZAI Hiroyuki
  • 山本 憲太朗 YAMAMOTO Kentaro
  • 尾山 和彦 OYAMA Kazuhiko
  • 土田 麻里子 TSUCHIDA Mariko
  • 後藤 公彦 GOTO Kimihiko
  • 三冨 正明 MITOMI Masaaki
Agents
  • 勝沼 宏仁 KATSUNUMA Hirohito
Priority Data
2010-01472726.01.2010JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) METHOD FOR MANUFACTURING A PYRIPYROPENE
(FR) PROCÉDÉ DE FABRICATION DE PYRIPYROPÈNE
(JA) ピリピロペンの製造法
Abstract
(EN) Provided is a method for manufacturing a pyripyropene by culturing a microorganism, created by the introduction of a specific polynucleotide or a recombinant vector comprising same, together with an intermediate compound necessary for the biosynthesis of pyripyropene A.
(FR) Procédé de fabrication d'une pyripyropène consistant à cultiver un micro-organisme créé par l'introduction d'un polynucléotide spécifique ou d'un vecteur de recombinaison contenant ce polynucléotide, avec un composé intermédiaire nécessaire à la biosynthèse de la pyripyropène A.
(JA)  特定のポリヌクレオチドまたはそれを含んでなる組換えベクターを導入してなる微生物を、ピリピロペンAの生合成に必要な中間化合物とともに培養する方法が提供される。本発明の方法により、ピリピロペンが製造できる。
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