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1. WO2011089456 - NOVEL MEDICINAL COMPOUNDS

Publication Number WO/2011/089456
Publication Date 28.07.2011
International Application No. PCT/HU2011/000008
International Filing Date 21.01.2011
IPC
C07D 241/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
241Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
02not condensed with other rings
04having no double bonds between ring members or between ring members and non-ring members
A61K 31/495 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
A61K 31/496 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
A61P 31/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
06for tuberculosis
CPC
A61P 31/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
06for tuberculosis
C07D 215/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
215Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
02having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
12with substituted hydrocarbon radicals attached to ring carbon atoms
C07D 235/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
C07D 295/096
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
295Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2.] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
04with substituted hydrocarbon radicals attached to ring nitrogen atoms
08substituted by singly bound oxygen or sulfur atoms
096with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
C07D 307/79
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77ortho- or peri-condensed with carbocyclic rings or ring systems
78Benzo [b] furans; Hydrogenated benzo [b] furans
79with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals directly attached to carbon atoms of the hetero ring
Applicants
  • URATIM GYÁRTÓ KORLÁTOLT FELELŐSSÉGŰ TÁRSASÁG [HU]/[HU] (AllExceptUS)
  • CSONKA, István [HU]/[HU] (UsOnly)
  • GROLMUSZ, Vince [HU]/[HU] (UsOnly)
  • RÉPÁSI, József [HU]/[HU] (UsOnly)
  • SZABADKA, Zoltán [HU]/[HU] (UsOnly)
  • SZABÓ, András [HU]/[HU] (UsOnly)
  • KERTÉSZ, Máriusz [HU]/[HU] (UsOnly)
Inventors
  • CSONKA, István
  • GROLMUSZ, Vince
  • RÉPÁSI, József
  • SZABADKA, Zoltán
  • SZABÓ, András
  • KERTÉSZ, Máriusz
Agents
  • KOVÁRI, Zoltán
Priority Data
P100003321.01.2010HU
Publication Language English (EN)
Filing Language Hungarian (HU)
Designated States
Title
(EN) NOVEL MEDICINAL COMPOUNDS
(FR) NOUVEAUX COMPOSÉS MÉDICINAUX
Abstract
(EN)
The invention concerns novel compounds possessing the general formula (I), pharmaceutical compositions containing any of these compounds as active ingredient, and preparation of these compounds, where R, Q, and A are defined in the claims. The new compounds are efficient in order to prevent and/or treat diseases caused by the bacterium Mycobacterium tuberculosis or any other Mycobacteria.
(FR)
L'invention concerne des nouveaux composés médicinaux représentés par la formule générale (I), des compositions pharmaceutiques contenant l'un quelconque de ces composés en tant que principe actif, et la préparation de ces composés; R, Q et A étant tels que définis dans les revendications. Les nouveaux composés sont efficaces pour empêcher et/ou traiter des maladies provoquées par la bactérie Mycobacterium tuberculosis ou toute autre mycobactérie.
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