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1. (WO2011088076) STRUCTURED RNA MOTIFS AND COMPOUNDS AND METHODS FOR THEIR USE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2011/088076 International Application No.: PCT/US2011/020933
Publication Date: 21.07.2011 International Filing Date: 12.01.2011
IPC:
C12N 15/67 (2006.01) ,C12N 15/113 (2010.01) ,C12N 15/115 (2010.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
67
General methods for enhancing the expression
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
113
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
115
Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith
Applicants:
YALE UNIVERSITY [US/US]; Two Whitney Avenue New Haven, CT 06510, US (AllExceptUS)
BREAKER, Ronald, R. [US/US]; US (UsOnly)
WEINBERG, Zasha [US/US]; US (UsOnly)
Inventors:
BREAKER, Ronald, R.; US
WEINBERG, Zasha; US
Agent:
TERAPANE, Michael, J.; Pabst Patent Group LLP 1545 Peachtree Street, N.E., Suite 320 Atlanta, GA 30309, US
Priority Data:
61/335,85212.01.2010US
Title (EN) STRUCTURED RNA MOTIFS AND COMPOUNDS AND METHODS FOR THEIR USE
(FR) MOTIFS ET COMPOSÉS ARN STRUCTURÉS ET LEURS PROCÉDÉS D'UTILISATION
Abstract:
(EN) Disclosed are compositions and methods involing riboswitches and RNA motis. For example, disclosed are compositions and methods involving glutamine-responsive riboswitches, S-adenosylmethionine-repsonsive riboswitches, S-adenosylhomocysteine- repsonsive riboswitches, glutamine riboswitches, SAM/SAH riboswitches, glnA riboswitches, Downstream-peptide riboswitches, crcB riboswitches, pfl riboswitches, yjdF riboswitches, manA riboswitches, wcaG riboswitches, epsC riboswitches, ykkC-III riboswitches, psaA riboswitches, psbA riboswitches, PhotoRC-I riboswitches, PhotoRC-II riboswitches, and psbNH riboswitches.
(FR) Cette invention concerne des compositions et des procédés impliquant des riborégulateurs et des motifs ARN. Par exemple, des compositions et des procédés impliquant des riborégulateurs sensibles à la glutamine, des riborégulateurs sensibles à l'adénosylméthionine, des riborégulateurs sensibles à la S-adénosylhomocystéine, des riborégulateurs de glutamine, des riborégulateurs SAM/SAH, des riborégulateurs glnA, des riborégulateurs de peptide aval, des riborégulateurs crcB, des riborégulateurs pfl, des riborégulateurs yjdF, des riborégulateurs manA, des riborégulateurs wcaG, des riborégulateurs epsC, des riborégulateurs ykkC-III, des riborégulateurs psaA, des riborégulateurs psbA, des riborégulateurs PhotoRC-I, des riborégulateurs PhotoRC-II, et des riborégulateurs psbNH sont décrits.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)