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1. (WO2011080050) CCL21 BINDING MOLECULES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2011/080050 International Application No.: PCT/EP2010/069430
Publication Date: 07.07.2011 International Filing Date: 10.12.2010
IPC:
C07K 16/24 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
24
against cytokines, lymphokines or interferons
Applicants:
NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel, CH (AllExceptUS)
BARDROFF, Michael [DE/CH]; CH (UsOnly)
EWERT, Stefan [DE/CH]; CH (UsOnly)
JAEGER, Ute [DE/DE]; DE (UsOnly)
JARAI, Gabor [HU/GB]; GB (UsOnly)
KUNZ, Christian Carsten Silvester [DE/DE]; DE (UsOnly)
WIESEHAN, Katja [DE/DE]; DE (UsOnly)
Inventors:
BARDROFF, Michael; CH
EWERT, Stefan; CH
JAEGER, Ute; DE
JARAI, Gabor; GB
KUNZ, Christian Carsten Silvester; DE
WIESEHAN, Katja; DE
Agent:
KASSOW, Anders; Novartis Pharma AG Patent Department CH-4002 Basel, CH
Priority Data:
61/285,63211.12.2009US
61/285,63411.12.2009US
Title (EN) CCL21 BINDING MOLECULES
(FR) MOLÉCULES DE LIAISON
Abstract:
(EN) The present invention relates to binding molecules, in particular antibodies and immunoglobulins to human CCL21 (hCCL21) and their use in the treatment and/or prevention of human diseases and disorders, particularly those of a fibrotic nature. Pharmaceutical compositions, methods of manufacture and methods of treatment are also disclosed.
(FR) La présente invention concerne des molécules de liaison, en particulier des anticorps et des immunoglobulines de la CCL21 humaine (hCCL21), ainsi que leur utilisation pour traiter et/ou prévenir des maladies et affections humaines, en particulier de nature fibrogène. L'invention concerne également des compositions pharmaceutiques, des procédés de fabrication et des méthodes de traitement.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)