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1. WO2011077347 - ACTIVE INGREDIENT DELIVERY SYSTEM

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Publication Number WO/2011/077347
Publication Date 30.06.2011
International Application No. PCT/IB2010/055938
International Filing Date 20.12.2010
IPC
A23L 1/00 2006.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1Foods or foodstuffs; Their preparation or treatment
A23L 1/025 2006.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1Foods or foodstuffs; Their preparation or treatment
025Physical treatment, e.g. with wave energy, irradiation, electrical means, magnetic fields
A23L 1/09 2006.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1Foods or foodstuffs; Their preparation or treatment
09containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
A61K 9/16 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
16Agglomerates; Granulates; Microbeadlets
A61K 8/04 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
04Dispersions; Emulsions
A23L 1/22 2006.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1Foods or foodstuffs; Their preparation or treatment
22Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes
CPC
A23G 3/36
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
3Sweetmeats; Confectionery; Marzipan; Coated or filled products
34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
36characterised by the composition ; containing organic or inorganic compounds
A23G 4/06
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
06characterised by the composition ; containing organic or inorganic compounds
A23G 4/20
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
4Chewing gum
18characterised by shape, structure or physical form, e.g. aerated products
20Composite products, e.g. centre-filled ; , multi-layer, laminated
A23L 27/10
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
10Natural spices, flavouring agents or condiments; Extracts thereof
A23L 27/70
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
70Fixation, conservation, or encapsulation of flavouring agents
A23L 27/72
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
27Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
70Fixation, conservation, or encapsulation of flavouring agents
72Encapsulation
Applicants
  • FIRMENICH SA [CH]/[CH] (AllExceptUS)
  • GREGSON, Christopher [GB]/[US] (UsOnly)
  • SILLICK, Matthew [US]/[US] (UsOnly)
Inventors
  • GREGSON, Christopher
  • SILLICK, Matthew
Agents
  • DALE, Gavin
Priority Data
09180719.824.12.2009EP
61/288,92122.12.2009US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ACTIVE INGREDIENT DELIVERY SYSTEM
(FR) DISPOSITIF D'ADMINISTRATION D'UN PRINCIPE ACTIF
Abstract
(EN) A spray-chilled particulate delivery system that has a crystalline matrix structure and comprises a volatile hydrophobic active ingredient and a carrier material selected from the group consisting of erythritol and mannitol and mixtures thereof wherein, relative to the total weight of the carrier material, 75% or more of the carrier material is in crystalline form. The process for preparing the delivery system comprises the steps of (i) forming a melt of a carrier material selected from the group consisting of erythritol and mannitol and mixtures thereof (ii) incorporating a volatile hydrophobic active ingredient into the melt (iii) forming a melt-mixture comprising an emulsion, dispersion or suspension of the volatile hydrophobic active ingredient in the melt (iv) forming discrete particles of the melt mixture, and (v) cooling the discrete particles, so as to form the crystalline delivery system.
(FR) La présente invention concerne un dispositif d'administration à base de particules réfrigérées par atomisation présentant une structure de type matrice cristalline et comprenant un principe actif hydrophobe volatile et un excipient choisi dans le groupe constitué de l'érythritol, du mannitol et des mélanges de ceux-ci, au moins 75 % de l'excipient, sur la base de son poids total, se présentant sous une forme cristalline. Le procédé de fabrication dudit dispositif d'administration comprend les étapes consistant (i) à faire fondre un excipient choisi dans le groupe constitué de l'érythritol, du mannitol et des mélanges de ceux-ci, (ii) à y incorporer un principe actif hydrophobe volatile, (iii) à préparer un mélange fondu constitué d'une émulsion, d'une dispersion ou d'une suspension du principe actif hydrophobe volatile dans l'excipient fondu, (iv) à préparer des particules discrètes dudit mélange et (v) à faire refroidir lesdites particules discrètes de façon à obtenir ledit dispositif d'administration cristallin.
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