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1. WO2011072509 - PROGESTERONE FORMULATION COMPOSITION AND PREPARATION METHOD THEREOF

Publication Number WO/2011/072509
Publication Date 23.06.2011
International Application No. PCT/CN2010/072728
International Filing Date 13.05.2010
IPC
A61K 9/48 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A61K 31/57 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
A61P 5/34 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
5Drugs for disorders of the endocrine system
24of the sex hormones
34Gestagens
A61P 15/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders; Contraceptives
06Antiabortive agents; Labour repressants
A61P 15/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders; Contraceptives
12for climacteric disorders
CPC
A61K 31/57
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
57substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
A61K 35/644
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
56Materials from animals other than mammals
63Arthropods
64Insects, e.g. bees, wasps or fleas
644Beeswax; Propolis; Royal jelly; Honey
A61K 47/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
A61K 9/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
08Solutions
A61K 9/4875
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
4841Filling excipients; Inactive ingredients
4875Compounds of unknown constitution, e.g. material from plants or animals
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
Applicants
  • 浙江爱生药业有限公司 ZHEJIANG ASEN PHARMACEUTICAL CO., LTD. [CN]/[CN] (AllExceptUS)
  • 邓金明 DENG, Jinming [CN]/[CN]
  • 吴海英 WU, Haiying [CN]/[CN]
Inventors
  • 邓金明 DENG, Jinming
  • 吴海英 WU, Haiying
Agents
  • 北京海虹嘉诚知识产权代理有限公司 BEIJING HAIHONG JIACHENG INTELLECTUAL PROPERTY & PARTNERS
Priority Data
200910249693.714.12.2009CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) PROGESTERONE FORMULATION COMPOSITION AND PREPARATION METHOD THEREOF
(FR) COMPOSITION DE FORMULATION DE PROGESTÉRONE ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
(ZH) 黄体酮制剂组合物及其制备方法
Abstract
(EN)
A progesterone formulation composition and the preparation method thereof are disclosed. The composition is composed of progesterone oil content prepared from progesterone, non-polar solvents and solubilizers and encapsulating materials. The non-polar solvents are vegetable oils or/and animal oils. The solubilizer is lecithin or/and beeswax. Said composition can be administered orally for the treatment of diseases or disorders induced by progestogen insufficiency or inadequate luteal function.
(FR)
La présente invention concerne une composition de formulation de progestérone et son procédé de préparation associé. La composition se compose d'une partie huileuse de progestérone préparée à partir de progestérone, de solvants non polaires et de solubilisants ainsi que de substances d'encapsulation. Les solvants non polaires sont des huiles végétales et/ou animales. Le solubilisant est la lécithine et/ou la cire d'abeille. Ladite composition peut être administrée par voie orale pour le traitement de maladies ou de troubles induits par une insuffisance progestative ou une fonction lutéale inadaptée.
Also published as
Latest bibliographic data on file with the International Bureau