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1. (WO2011070005) EGFR AND PTEN GENE ALTERATIONS PREDICTS SURVIVAL IN PATIENTS WITH BRAIN TUMORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2011/070005 International Application No.: PCT/EP2010/069058
Publication Date: 16.06.2011 International Filing Date: 07.12.2010
Chapter 2 Demand Filed: 07.10.2011
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
DONOVAN, Michael J. [ES/ES]; ES (UsOnly)
COLOMER VALERO, Anna [ES/ES]; ES (UsOnly)
ERILL SAGALÉS, Nadina [ES/ES]; ES (UsOnly)
FERRER ABIZANDA, Isidre [ES/ES]; ES (UsOnly)
BOLUDA CASAS, Susana [ES/ES]; ES (UsOnly)
EUROPATH BIOSCIENCES, S.L. [ES/ES]; Provença, 392 planta baja E-08025 Barcelona, ES (AllExceptUS)
Inventors:
DONOVAN, Michael J.; ES
COLOMER VALERO, Anna; ES
ERILL SAGALÉS, Nadina; ES
FERRER ABIZANDA, Isidre; ES
BOLUDA CASAS, Susana; ES
Agent:
ARIAS SANZ, Juan; ABG Patentes, S.L. Avenida de Burgos 16D Edificio Euromor E-28036 Madrid, ES
Priority Data:
09382271.607.12.2009EP
Title (EN) EGFR AND PTEN GENE ALTERATIONS PREDICTS SURVIVAL IN PATIENTS WITH BRAIN TUMORS
(FR) DES ALTÉRATIONS DES GÈNES EGFR ET PTEN PRÉDISENT LA SURVIE CHEZ DES PATIENTS AYANT DES TUMEURS CÉRÉBRALES
Abstract:
(EN) The invention relates to methods of predicting the clinical outcome of brain cancer patients based on the LOH levels of the PTEN gene and on the expression levels or the polysomy / amplification levels of EGFR gene in a sample from said patients.
(FR) L'invention concerne des procédés de prédiction du résultat clinique de patients atteints d'un cancer cérébral sur la base des taux LOH du gène PTEN et des taux d'expression ou des taux de polysomie / amplification du gène EGFR dans un échantillon provenant desdits patients.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)