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1. (WO2011069082) RED BLOOD CELL-MIMETIC PARTICLES AND METHODS FOR MAKING AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/069082    International Application No.:    PCT/US2010/058921
Publication Date: 09.06.2011 International Filing Date: 03.12.2010
IPC:
A61K 47/48 (2006.01), A61K 47/30 (2006.01), A61K 9/24 (2006.01), A61K 9/52 (2006.01), A61K 49/18 (2006.01), A61K 49/08 (2006.01), A61K 35/18 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN [US/US]; 1600 Huron Parkway, 2nd Floor Ann Arbor, Michigan 48109-2590 (US) (For All Designated States Except US).
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street Twelfth Floor Oakland, California 94607-5200 (US) (For All Designated States Except US).
LAHANN, Joerg [DE/US]; (US) (For US Only).
MITRAGOTRI, Samir [US/US]; (US) (For US Only).
BHASKAR, Srijanani [IN/US]; (US) (For US Only).
DOSHI, Nishit [IN/US]; (US) (For US Only).
ZAHR, Alisar S. [US/US]; (US) (For US Only)
Inventors: LAHANN, Joerg; (US).
MITRAGOTRI, Samir; (US).
BHASKAR, Srijanani; (US).
DOSHI, Nishit; (US).
ZAHR, Alisar S.; (US)
Agent: WOODSIDE-WOJTALA, Jennifer M.; Harness, Dickey & Pierce, P.L.C. P.O. Box 828 Bloomfield Hills, Michigan 48303 (US)
Priority Data:
61/266,927 04.12.2009 US
Title (EN) RED BLOOD CELL-MIMETIC PARTICLES AND METHODS FOR MAKING AND USE THEREOF
(FR) PARTICULES MIMÉTIQUES DES ÉRYTHROCYTES ET LEURS PROCÉDÉS DE RÉALISATION ET D'UTILISATION
Abstract: front page image
(EN)The present technology provides synthesized particles that mimic key structural and functional features of red blood cells. Such RBC-mimicking particles possess the ability to carry oxygen (and carbon dioxide) and flow through capillaries smaller than their own diameter. Further, such particles can also deliver drugs and imaging agents. These particles provide a new paradigm for the design of drug delivery and imaging carriers since they combine the functionality of natural RBCs with the broad applicability and versatility of synthetic drug delivery particles. Further, such particles can be used for detoxification and other biomedical applications.
(FR)La présente invention concerne des particules synthétisées qui imitent les caractéristiques structurelles et fonctionnelles essentielles des érythrocytes. De telles particules qui imitent les érythrocytes possèdent la capacité de transporter l'oxygène (et le dioxyde de carbone) et de s'écouler à travers des capillaires d'un diamètre inférieur à leur propre diamètre. En outre, de telles particules peuvent également administrer des médicaments et des agents d'imagerie. Lesdites particules offrent un nouveau paradigme pour la conception d'une administration de médicament et de supports d'imagerie, car elles combinent la fonctionnalité des érythrocytes naturels au vaste champ d'application et à la polyvalence de particules d'administration de médicaments synthétiques. En outre, ces particules peuvent être utilisées pour la détoxication et d'autres applications biomédicales.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)