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1. (WO2011055215) NOVEL BENZOPYRAN KINASE MODULATORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2011/055215 International Application No.: PCT/IB2010/002804
Publication Date: 12.05.2011 International Filing Date: 03.11.2010
IPC:
C07D 311/34 (2006.01) ,C07D 405/06 (2006.01) ,C07D 487/04 (2006.01) ,A61K 31/519 (2006.01) ,A61K 31/52 (2006.01) ,A61P 35/00 (2006.01) ,A61P 37/06 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
311
Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02
ortho- or peri-condensed with carbocyclic rings or ring systems
04
Benzo [b] pyrans, not hydrogenated in the carbocyclic ring
22
with oxygen or sulfur atoms directly attached in position 4
26
with aromatic rings attached in position 2 or 3
34
with aromatic rings attached in position 3 only
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
52
Purines, e.g. adenine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
06
Immunosuppressants, e.g. drugs for graft rejection
Applicants:
RHIZEN PHARMACEUTICALS SA [CH/CH]; Fritz Courvoisier 40 CH-2300 La Chaux-de-Fonds, CH (AllExceptUS)
MUTHUPPALANIAPPAN, Meyyappan [IN/IN]; IN (UsOnly)
VISWANADHA, Srikant [IN/IN]; IN (UsOnly)
BABU, Govindarajulu [IN/IN]; IN (UsOnly)
VAKKALANKA, Swaroop Kumar V.S. [IN/CH]; CH (UsOnly)
Inventors:
MUTHUPPALANIAPPAN, Meyyappan; IN
VISWANADHA, Srikant; IN
BABU, Govindarajulu; IN
VAKKALANKA, Swaroop Kumar V.S.; CH
Priority Data:
1429/CHE/201024.05.2010IN
2690/CHE/200905.11.2009IN
61/364,66115.07.2010US
Title (EN) NOVEL BENZOPYRAN KINASE MODULATORS
(FR) NOUVEAUX MODULATEURS DE KINASE
Abstract:
(EN) The present invention provides PL3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.
(FR) La présente invention concerne des modulateurs de protéine kinase PI3K, des procédés de préparation de ceux-ci, des compositions pharmaceutiques contenant ceux-ci et des procédés de traitement, prévention et/ou amélioration de maladies ou troubles médiés par des kinases avec ceux-ci.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
SG180712IL219585EP2496567JP2013510133CA2779574EA201290209
KR1020120104226CN102812013EP3050876NZ599830AU2010316780BR112012010640
ID2012/05161MYPI 2012002000PH1/2012/500901TH138068ES2651682KR1020180010322
PH1/2015/501806