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199. (WO2011051452) N-CONTAINING HETEROARYL DERIVATIVES AS JAK3 KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2011/051452 International Application No.: PCT/EP2010/066476
Publication Date: 05.05.2011 International Filing Date: 29.10.2010
IPC:
C07D 519/04 (2006.01) ,A61K 31/52 (2006.01) ,A61K 31/522 (2006.01) ,A61P 29/00 (2006.01) ,A61P 35/00 (2006.01) ,A61P 37/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
519
Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/ or C07D455/257
04
Dimeric indole alkaloids, e.g. vincaleucoblastine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
52
Purines, e.g. adenine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
52
Purines, e.g. adenine
522
having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
Applicants:
ALMANSA ROSALES, Carmen [ES/ES]; ES (UsOnly)
SALAS SOLANA, Jorge [ES/ES]; ES (UsOnly)
SOLIVA SOLIVA, Robert [ES/ES]; ES (UsOnly)
RODRÍGUEZ ESCRICH, Sergio [ES/ES]; ES (UsOnly)
SICRE GONZÁLEZ, María Cristina [ES/ES]; ES (UsOnly)
PALAU PHARMA, S.A. [ES/ES]; Av. Camí Reial, 51-57 Palau-Solità i Plegamans E-08184 Barcelona, ES (AllExceptUS)
Inventors:
ALMANSA ROSALES, Carmen; ES
SALAS SOLANA, Jorge; ES
SOLIVA SOLIVA, Robert; ES
RODRÍGUEZ ESCRICH, Sergio; ES
SICRE GONZÁLEZ, María Cristina; ES
Agent:
WIEDEMANN, Peter; Hoffmann . Eitle Arabellastrasse 4 81925 Munich, DE
Priority Data:
09382233.629.10.2009EP
61/291,05130.12.2009US
61/329,92730.04.2010US
Title (EN) N-CONTAINING HETEROARYL DERIVATIVES AS JAK3 KINASE INHIBITORS
(FR) DÉRIVÉS HÉTÉROARYLES CONTENANT N EN TANT QU'INHIBITEURS DE KINASE JAK3
Abstract:
(EN) N-containing heteroaryl derivatives of formula I or II, wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as JAK, particularly JAK3, kinase inhibitors.
(FR) L'invention concerne des dérivés hétéroaryles contenant N de formule I ou II, dans lesquels les significations des divers substituants sont divulguées dans la description. Ces composés sont utiles en tant qu'inhibiteurs de kinase JAK, en particulier JAK3.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)