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1. (WO2011050194) METHODS AND COMPOSITIONS FOR MODULATING HEPSIN ACTIVATION OF MACROPHAGE-STIMULATING PROTEIN
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2011/050194 International Application No.: PCT/US2010/053600
Publication Date: 28.04.2011 International Filing Date: 21.10.2010
IPC:
A61K 39/395 (2006.01) ,C12Q 1/37 (2006.01) ,G01N 33/53 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
34
involving hydrolase
37
involving peptidase or proteinase
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
Applicants:
GENENTECH, INC. [US/US]; 1 DNA Way South San Francisco, California 94080, US (AE, AG, AM, AO, AU, AZ, BA, BB, BF, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CI, CL, CM, CO, CR, CU, DM, DO, DZ, EC, EG, GA, GD, GE, GH, GM, GN, GQ, GT, GW, HN, ID, IL, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LY, MA, MD, ME, MG, ML, MN, MR, MW, MX, MY, MZ, NA, NE, NG, NI, NZ, OM, PE, PG, PH, RU, SC, SD, SG, SL, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW)
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel, CH (AL, AT, BE, BG, CH, CN, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IN, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
GANESAN, Rajkumar [IN/US]; US (UsOnly)
KIRCHHOFER, Daniel [US/US]; US (UsOnly)
Inventors:
GANESAN, Rajkumar; US
KIRCHHOFER, Daniel; US
Agent:
COBURN, Cara, M.; GENENTECH, INC. 1 DNA Way MS 49 South San Francisco, California 94080, US
Priority Data:
61/253,99022.10.2009US
Title (EN) METHODS AND COMPOSITIONS FOR MODULATING HEPSIN ACTIVATION OF MACROPHAGE-STIMULATING PROTEIN
(FR) PROCÉDÉS ET COMPOSITIONS POUR MODULER L'ACTIVATION D'HEPSINE D'UNE PROTÉINE DE STIMULATION DE MACROPHAGE
Abstract:
(EN) The invention provides methods and compositions for modulating hepsin activity and the MSP/Ron pathway, in particular by regulating pro-MSP activation by hepsin.
(FR) L'invention concerne des procédés et compositions visant à moduler l'activité d'hepsine et le chemin MSP/Ron, en particulier en régulant l'activation pro-MSP par l'hepsine.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2490718US20120282271JP2013507967CN102711826CA2778442RU2012120863
MX2012004617RU0002539772KR1020120105446ES2564207BR112012009409IN3566/CHENP/2012