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1. (WO2011022074) RIBOFLAVIN BASED AEROSOL AND USE AS PLACEBO IN TRIALS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/022074    International Application No.:    PCT/US2010/002306
Publication Date: 24.02.2011 International Filing Date: 19.08.2010
IPC:
G01N 33/15 (2006.01), A61K 31/525 (2006.01), A61K 31/7088 (2006.01), A61K 9/12 (2006.01), A61K 31/706 (2006.01)
Applicants: MPEX PHARMACEUTICALS, INC. [US/US]; 11535 Sorrento Valley Road San Diego, CA 92121 (US) (For All Designated States Except US).
GRIFFITH, David, C. [US/US]; (US) (For US Only)
Inventors: GRIFFITH, David, C.; (US)
Agent: MALLON, Joseph, J.; Knobbe Martens Olson & Bear LLP 2040 Main Street 14th Floor Irvine, CA 92614 (US)
Priority Data:
61/249,228 06.10.2009 US
61/235,319 19.08.2009 US
Title (EN) RIBOFLAVIN BASED AEROSOL AND USE AS PLACEBO IN TRIALS
(FR) AÉROSOL À BASE DE RIBOFLAVINE ET UTILISATION COMME PLACEBO LORS D'ESSAIS
Abstract: front page image
(EN)A method for evaluating an aerosolized test compound includes administering a test compound to a first population of individuals, via inhalation of an aerosol; administering a placebo comprising riboflavin 5 '-phosphate to a second population of individuals, via inhalation of an aerosol; and comparing a biological marker for individuals in the two populations. An aerosol comprising riboflavin 5 '-phosphate (also known as flavin mononucleotide) may be used either as a placebo in clinical trials, or therapeutically.
(FR)L'invention concerne un procédé d'évaluation d'un composé de test sous forme d'aérosol. Le procédé comprend l'administration d'un composé de test à une première population d'individus, par inhalation d'un aérosol ; l'administration d'un placebo contenant le 5'-phosphate de riboflavine à une deuxième population d'individus, par inhalation d'un aérosol ; et la comparaison d'un marqueur biologique chez les individus des deux populations. Un aérosol comprenant le 5'-phosphate de riboflavine (également appelé mononucléotide flavine) peut être utilisé comme placebo lors d'essais cliniques, ou de manière thérapeutique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)