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1. (WO2011021833) COMPOSITION FOR PREVENTING OR TREATING INFLAMMATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/021833    International Application No.:    PCT/KR2010/005420
Publication Date: 24.02.2011 International Filing Date: 17.08.2010
IPC:
A61K 38/08 (2006.01), A61P 29/00 (2006.01), A61P 19/02 (2006.01), A61P 11/00 (2006.01)
Applicants: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE [KR/KR]; Kyunghee Univ. Global Campus, Seocheon-dong, 1, Giheung-gu, Yongin-si, Gyeonggi-do 446-701 (KR) (For All Designated States Except US).
SON, Young Sook [KR/KR]; (KR) (For US Only).
HONG, Hyun Sook [KR/KR]; (KR) (For US Only).
KIM, Do Yeon [KR/KR]; (KR) (For US Only).
LEE, Eun Kyung [KR/KR]; (KR) (For US Only)
Inventors: SON, Young Sook; (KR).
HONG, Hyun Sook; (KR).
KIM, Do Yeon; (KR).
LEE, Eun Kyung; (KR)
Agent: AHN, So-Young; Dr. Ahn International Patent Law Office 10th Fl., Shinseung Bldg. 1676-1, Seocho-dong Seocho-gu, Seoul 137-881 (KR)
Priority Data:
10-2009-0075881 17.08.2009 KR
Title (EN) COMPOSITION FOR PREVENTING OR TREATING INFLAMMATION
(FR) COMPOSITION DESTINÉE À LA PRÉVENTION OU AU TRAITEMENT D'UNE INFLAMMATION
(KO) 염증 예방 또는 치료용 조성물
Abstract: front page image
(EN)The present invention relates to a composition containing substance P for preventing or treating inflammation. The composition containing substance P according to the present invention exhibits the effect of decreasing leukocytes, neutrophils and hematopoietic stem cells in blood, which are associated with inflammation, and of increasing anti-inflammatory cytokines, regulatory T-lymphocytes, anti-inflammatory macrophages and the like, thereby terminating inflammatory response at an early stage, and is thus highly effective in preventing and treating inflammation caused by a non-traumatic, traumatic, infectious or ischemic retinal injury.
(FR)La présente invention concerne une composition contenant une substance P destinée à prévenir ou à traiter une inflammation. La composition contenant la substance P selon la présente invention présente l'effet de faire diminuer les leucocytes, les neutrophiles et les cellules souches hématopoïétiques dans le sang, lesquels sont associés à une inflammation, et de faire augmenter les cytokines anti-inflammatoires, les lymphocytes T régulateurs, les macrophages anti-inflammatoires et équivalents, mettant ainsi un terme à la réponse inflammatoire à un stade précoce, et est ainsi très efficace pour prévenir et traiter une inflammation causée par une lésion rétinienne non traumatique, traumatique, infectieuse ou ischémique.
(KO)본 발명은 서브스턴스-P(Substance P, SP)를 포함하는 염증의 예방 및 치료용 조성물에 관한 것이다. 본 발명에 의한 서브스턴스-P를 포함하는 조성물은 염증 관련 백혈구, 호중구 및 조혈줄기세포를 혈액 내에 감소시키고, 항염증 관련 사이토카인, 조절 T 림파구, 항염증성 대식세포 등 증가시키는 효과가 있어 염증반응을 조기에 종료시켜 비외상성, 외상성, 감염성 허혈성 손상으로부터 염증을 예방 및 치료하는 탁월한 효과를 제공한다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)