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1. (WO2011021832) COMPOSITION FOR PREVENTING OR TREATING A SPINAL CORD INJURY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/021832    International Application No.:    PCT/KR2010/005419
Publication Date: 24.02.2011 International Filing Date: 17.08.2010
IPC:
A61K 38/10 (2006.01), A61P 25/00 (2006.01), A61P 25/28 (2006.01), A61P 25/16 (2006.01)
Applicants: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE [KR/KR]; Kyunghee Univ. Global Campus, Seocheon-dong, 1, Giheung-gu, Yongin-si Gyeonggi-do 446-701 (KR) (For All Designated States Except US).
SON, Young Sook [KR/KR]; (KR) (For US Only).
JIANG, Mei Hua [CN/KR]; (KR) (For US Only)
Inventors: SON, Young Sook; (KR).
JIANG, Mei Hua; (KR)
Agent: AHN, So-Young; Dr. Ahn International Patent Law Office 10th Fl., Shinseung Bldg. 1676-1, Seocho-dong Seocho-gu Seoul 137-881 (KR)
Priority Data:
10-2009-0075880 17.08.2009 KR
Title (EN) COMPOSITION FOR PREVENTING OR TREATING A SPINAL CORD INJURY
(FR) COMPOSITION POUR PRÉVENIR OU TRAITER UNE LÉSION DE LA MOELLE ÉPINIÈRE
(KO) 척수 손상 예방 또는 치료용 조성물
Abstract: front page image
(EN)The present invention relates to a novel use of substance P. The substance P of the present invention exhibits the effects of decreasing microglia activity, decreasing proinflammatory cytokines, inhibiting apoptosis, etc. The substance P of the present invention effectively treats degenerative central nervous system diseases or disorders such as a spinal cord injury caused by a traumatic injury (flexion injury, vertical compression injury, hyperextension injury, flexion-rotation injury) and by a non-traumatic injury (vascular dysfunction, arthritis, or degenerative arthritis), Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, depressive disorder, epilepsy, etc.
(FR)La présente invention concerne une nouvelle utilisation d'une substance P. Ladite substance présente les effets de réduire l'activité des cellules microgliales, de réduire les cytokines pro-inflammatoires, d'inhiber l'apoptose, etc. La substance P de la présente invention traite efficacement les maladies ou les troubles dégénératifs du système nerveux central de type lésion de la moelle épinière provoquée par une lésion traumatiqe (lésion par flexion, lésion par compression verticale, lésion par hyperextension, lésion par flexion-rotation) et par une lésion non traumatique (anomalie vasculaire, arthrite, ou arthrose), la maladie de Parkinson, la maladie d'Alzheimer, la sclérose latérale amyotrophique, la maladie de Huntington, le trouble dépressif, l'épilepsie, etc.
(KO)본 발명은 서브스턴스-P(Substance P, 서브스턴스 P)의 신규용도에 관한 것이 다. 본 발명에 의한 서브스턴스-P는 소교세포 활성 감소 작용, 염증유발 싸이토카 인 감소, 세포자멸사 억제 등의 효과를 나타내며, 외상성 손상(굴곡손상, 수직압박손 상, 과신전손상, 굴곡회전손상)과 비외상성 손상(혈관기능장애, 관절염이나 퇴행성관 절질환)으로 인한 척수손상, 파킨슨병, 알츠하이머병, 루게릭병, 헌팅톤병, 우울증, 간질병 등의 중추신경계 퇴행성 질환 등을 효과적으로 치료할 수 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)