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Machine translation
1. (WO2011019827) PHAGE DISPLAYING SYSTEM EXPRESSING SINGLE CHAIN ANTIBODY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/019827    International Application No.:    PCT/US2010/045184
Publication Date: 17.02.2011 International Filing Date: 11.08.2010
IPC:
C12P 21/06 (2006.01)
Applicants: ACADEMIA SINICA; N°. 128, Section 2, Academia Road, Nan-Kang, Taipei (TW) (For All Designated States Except US).
YANG, An-Suei [US/--]; (TW) (For US Only).
LEE, Yu-Ching; (TW) (For US Only).
CHEN, Ing-Chien; (TW) (For US Only).
YU, Chung-Ming; (TW) (For US Only).
HSU, Hung-Ju; (TW) (For US Only).
HUANG, Yi-Jen; (TW) (For US Only).
CHANG, Hung-Ju; (TW) (For US Only).
TSAI, Keng-Chang; (TW) (For US Only).
PENG, Hung-Pin; (TW) (For US Only)
Inventors: YANG, An-Suei; (TW).
LEE, Yu-Ching; (TW).
CHEN, Ing-Chien; (TW).
YU, Chung-Ming; (TW).
HSU, Hung-Ju; (TW).
HUANG, Yi-Jen; (TW).
CHANG, Hung-Ju; (TW).
TSAI, Keng-Chang; (TW).
PENG, Hung-Pin; (TW)
Agent: TSAO, Rocky, Y.; Occhiuti Rohlicek & Tsao LLP 10 Fawcett Street Cambridge, Massachusetts 02138 (US)
Priority Data:
61/232,819 11.08.2009 US
Title (EN) PHAGE DISPLAYING SYSTEM EXPRESSING SINGLE CHAIN ANTIBODY
(FR) SYSTÈME D'AFFICHAGE SUR PHAGE EXPRIMANT UN ANTICORPS À CHAÎNE UNIQUE
Abstract: front page image
(EN)Disclosed are nucleic acid libraries for identifying a signal peptide that facilitates production of disulfide-stabilized single chain antibody, and for facilitating production of a disulfide-stabilized single chain antibody. Also disclosed are host cell libraries and phage libraries including the nucleic acid libraries. Further disclosed are methods for identifying a signal peptide that facilitates production of disulfide- stabilized single chain antibody, and methods for producing a disulfide-stabilized single chain antibody and non-fusion form thereof.
(FR)L'invention concerne des banques d'acides nucléiques pour identifier un peptide signal, qui facilite la production d'un anticorps à chaîne unique, stabilisé par disulfure, et pour faciliter la production d'un anticorps à chaîne unique, stabilisé par disulfure. L'invention concerne également, des banques de cellules hôtes et des banques de phages comprenant les banques d'acides nucléiques. L'invention décrit en outre, des procédés d'identification d'un peptide signal, qui facilite la production d'un anticorps à chaîne unique, stabilisé par disulfure, et des procédés de production d'un anticorps à chaîne unique, stabilisé par disulfure et d'une forme non fusionnée de celui-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)