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1. (WO2011018504) IMMUNOMODULATORY COMPOSITIONS COMPRISING A POLYMER MATRIX AND AN OIL PHASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/018504    International Application No.:    PCT/EP2010/061791
Publication Date: 17.02.2011 International Filing Date: 12.08.2010
IPC:
A61K 9/16 (2006.01), A61K 9/50 (2006.01), A61K 39/00 (2006.01)
Applicants: SIGMOID PHARMA LIMITED [IE/IE]; The Invent Centre Dublin City University Dublin, Dublin 9 (IE) (For All Designated States Except US).
COULTER, Ivan [IE/IE]; (IE) (For US Only).
MCDONALD, Bernard Francis [IE/IE]; (IE) (For US Only).
AVERSA, Vincenzo [IT/IE]; (IE) (For US Only).
LAVELLE, Edward Charles [IE/IE]; (IE) (For US Only).
ROSA, Mónica Torres [PT/IE]; (IE) (For US Only)
Inventors: COULTER, Ivan; (IE).
MCDONALD, Bernard Francis; (IE).
AVERSA, Vincenzo; (IE).
LAVELLE, Edward Charles; (IE).
ROSA, Mónica Torres; (IE)
Agent: HARRISON GODDARD FOOTE; Belgrave Hall Belgrave Street Leeds LS2 8DD (GB)
Priority Data:
61/233,170 12.08.2009 US
IE 2009/0618 12.08.2009 IE
Title (EN) IMMUNOMODULATORY COMPOSITIONS COMPRISING A POLYMER MATRIX AND AN OIL PHASE
(FR) COMPOSITIONS IMMUNOMODULATRICES COMPRENANT UNE MATRICE POLYMÈRE ET UNE PHASE HUILEUSE
Abstract: front page image
(EN)A pharmaceutical composition comprising a water-soluble polymer matrix in which are dispersed droplets of oil, the composition comprising at least one immunomodulator selected from an adjuvant, an antigen or a combination thereof.A method of manufacturing shaped compositions comprises mixing an aqueous solution of a water-soluble polymer with an oil-based liquid to form a water-in-oil emulsion, at least one of the aqueous solution and the oil-based liquid comprising an antigen or an adjuvant or a combination thereof, and then causing or allowing the resultant suspension to solidify into one or more beads or other shaped elements.
(FR)L'invention concerne une composition pharmaceutique qui comprend une matrice polymère soluble dans l'eau dans laquelle des gouttelettes d'huile sont dispersées, la composition comprenant au moins un immunomodulateur choisi parmi un adjuvant, un antigène ou leur combinaison. Un procédé de fabrication de compositions façonnées comprend le mélange d'une solution aqueuse d'un polymère soluble dans l'eau avec un liquide à base d'huile pour former une émulsion eau dans huile, la solution aqueuse et/ou le liquide à base d'huile comprenant un antigène ou un adjuvant ou leur combinaison, puis la solidification de la suspension résultante en une ou plusieurs billes ou autres éléments façonnés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)