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Pub. No.:    WO/2011/016052    International Application No.:    PCT/IN2010/000510
Publication Date: 10.02.2011 International Filing Date: 02.08.2010
Chapter 2 Demand Filed:    31.05.2011    
C07C 227/04 (2006.01), C07C 227/32 (2006.01), C07C 227/34 (2006.01), C07C 229/08 (2006.01), C07H 13/04 (2006.01)
Applicants: HELVETICA INDUSTRIES (P) LIMITED [IN/IN]; A-1, Community Center Naraina Industrial Area-Phase II New Delhi 110 028 (IN) (For All Designated States Except US).
PRADHAN, B., S. [IN/IN]; (IN) (For US Only)
Inventors: PRADHAN, B., S.; (IN)
Agent: TRIPATHI, Vishal; D-22, 2nd Floor Panchsheel Enclave New Delhi 110 017 (IN)
Priority Data:
1614/DEL/2009 03.08.2009 IN
2283/DEL/2009 05.11.2009 IN
1221/DEL/2010 26.05.2010 IN
Abstract: front page image
(EN)The invention relates to a process for preparing a compound of formula (I): wherein said process comprises hydrogenation of a compound of formula (II): under alkaline conditions, wherein R represents hydrogen or a labile group capable of being converted to hydrogen. The invention also relates to intermediates used in said process, to the use of said intermediates in the preparation of pregabalin and to a process for resolving racemic compounds of formula (I).
(FR)La présente invention concerne un procédé de préparation d'un composé de formule (I), ledit procédé comprenant l'hydrogénation d'un composé de formule (II) dans des conditions alcalines; R représentant hydrogène ou un groupe labile pouvant être converti hydrogène. Cette invention porte également sur des intermédiaires utilisés dans ledit procédé, sur l'utilisation de ces intermédiaires dans la préparation de prégabaline et sur un procédé de résolution de composés racémiques de formule (I).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)