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Machine translation
1. (WO2011015922) A HIGHLY EFFICIENT PROCESS OF PURIFICATION AND PRODUCTION OF RECOMBINANT TNK-TPA (TENECTEPLASE)
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2011/015922 International Application No.: PCT/IB2010/001899
Publication Date: 10.02.2011 International Filing Date: 02.08.2010
IPC:
C07K 1/22 (2006.01) ,C07K 1/18 (2006.01) ,C07K 16/40 (2006.01) ,C07K 1/16 (2006.01) ,C07K 1/36 (2006.01)
Applicants: PATELL, Villoo Morawala[IN/IN]; IN (UsOnly)
GUZDER, Sami, N.[IN/IN]; IN (UsOnly)
MAITY, Sunit[IN/IN]; IN (UsOnly)
SHEKAR, Sunil[IN/IN]; IN (UsOnly)
CHITTA, Geetha, Dr[IN/IN]; IN (UsOnly)
BABU, Nabi, Dr.[IN/IN]; IN (UsOnly)
SRINIVASAN, Ragunath[IN/IN]; IN (UsOnly)
AVESTHAGEN LIMITED[IN/IN]; 9th Floor, Discoverer International Tech Park (ITPB) Whitefield Road Bangalore 560066 Karnataka, IN (AllExceptUS)
Inventors: PATELL, Villoo Morawala; IN
GUZDER, Sami, N.; IN
MAITY, Sunit; IN
SHEKAR, Sunil; IN
CHITTA, Geetha, Dr; IN
BABU, Nabi, Dr.; IN
SRINIVASAN, Ragunath; IN
Priority Data:
1847/CHE/200903.08.2009IN
Title (EN) A HIGHLY EFFICIENT PROCESS OF PURIFICATION AND PRODUCTION OF RECOMBINANT TNK-TPA (TENECTEPLASE)
(FR) PROCÉDÉ HAUTEMENT EFFICACE DE PURIFICATION ET DE PRODUCTION DE TNK-tPA DE RECOMBINAISON (TÉNECTÉPLASE)
Abstract:
(EN) The present invention relates to the use of novel fermentation and chromatographic procedures separately and jointly for the production of recombinant TNK-tPA, a thrombolytic agent in biologically active form from fluids, especially mammalian host cell culture supernatants. The recovery via the novel procedures can be very pertinent in downstream processing.
(FR) L'invention porte sur l'utilisation de nouvelles procédures de fermentation et chromatographiques, appliquées séparément et conjointement, en vue de la production de TNK-tPA de recombinaison, agent thrombolytique biologiquement actif obtenu à partir de fluides et en particulier de surnageants de cultures de cellules hôtes de mammifères. La récupération reposant sur ces nouvelles procédures peut être très intéressante dans des traitements en aval.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)