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Machine translation
1. (WO2011015591) IMMUNOGENIC COMPOSITION COMPRISING ANTIGENIC S. AUREUS PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/015591    International Application No.:    PCT/EP2010/061314
Publication Date: 10.02.2011 International Filing Date: 03.08.2010
Chapter 2 Demand Filed:    06.06.2011    
IPC:
A61K 39/085 (2006.01), A61K 39/116 (2006.01), C12N 15/62 (2006.01)
Applicants: GLAXOSMITHKLINE BIOLOGICALS S.A. [BE/BE]; Rue de l'Institut 89 B-1330 Rixensart (BE) (For All Designated States Except US).
CASTADO, Cindy [BE/BE]; (BE) (For US Only).
GERMAIN, Sophie, Marie, Jeanne, Valentine [BE/BE]; (BE) (For US Only).
GILBERT, Melanie [CA/BE]; (BE) (For US Only)
Inventors: CASTADO, Cindy; (BE).
GERMAIN, Sophie, Marie, Jeanne, Valentine; (BE).
GILBERT, Melanie; (BE)
Agent: JOHNSTON, Caroline, Louise; GlaxoSmithKline Global Patents CN925.1 980 Great West Road Brentford Middlesex TW8 9GS (GB)
Priority Data:
0913681.3 05.08.2009 GB
Title (EN) IMMUNOGENIC COMPOSITION COMPRISING ANTIGENIC S. AUREUS PROTEINS
(FR) COMPOSITION IMMUNOGÈNE COMPRENANT DES PROTÉINES S. AUREUS ANTIGÉNIQUES
Abstract: front page image
(EN)The present application relates to an immunogenic composition comprising a fragment of a staphylococcal lsd protein such as IsdA, IsdB, IsdC or IsdH which comprises a NEAT domain. Fusion proteins comprising a NEAT domain of a first staphylococcal lsd protein and a NEAT domain from a second lsd protein are also disclosed as well as fusion proteins comprising a NEAT domain of a staphylococcal lsd protein involved in an iron/heme uptake system and a ligand binding domain of a staphylococcal extracellular component binding protein, for example CIfA, CIfB, SdrC, SdrD or SdrE.
(FR)La présente invention concerne une composition immunogène qui comprend un fragment d'une protéine staphylococcique Isd telle qu'IsdA, IsdB, IsdC ou IsdH qui comprend un domaine NEAT. La présente invention concerne également des protéines de fusion comprenant un domaine NEAT d'une première protéine staphylococcique Isd et un domaine NEAT d'une seconde protéine Isd, ainsi que des protéines de fusion comprenant un domaine NEAT d'une protéine staphylococcique Isd impliquée dans un système de capture de l'hème/fer et un domaine de liaison du ligand d'une protéine de liaison du composant extracellulaire staphylococcique, par exemple CIfA, CIfB, SdrC, SdrD ou SdrE.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)