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1. (WO2011015325) FRUCTOSYL PEPTIDYL OXIDASE AND SENSOR FOR ASSAYING A GLYCATED PROTEIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/015325    International Application No.:    PCT/EP2010/004707
Publication Date: 10.02.2011 International Filing Date: 02.08.2010
Chapter 2 Demand Filed:    01.06.2011    
IPC:
C12Q 1/00 (2006.01), C12Q 1/26 (2006.01), G01N 33/72 (2006.01)
Applicants: ROCHE DIAGNOSTICS GMBH [DE/DE]; Sandhofer Strasse 116 68305 Mannheim (DE) (DE only).
F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel (CH) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
ULTIZYME INTERNATIONAL, LTD. [JP/JP]; 1-13-16 Minami, Meguro Tokyo 152-0013 (JP) (For All Designated States Except US).
SODE, Koji [JP/JP]; (JP) (For US Only).
IKEBUKURO, Kazunori [JP/JP]; (JP) (For US Only)
Inventors: SODE, Koji; (JP).
IKEBUKURO, Kazunori; (JP)
Agent: WEBER, Manfred; Roche Diagnostics GmbH Patent Department 68298 Mannheim (DE)
Priority Data:
09009968.0 03.08.2009 EP
Title (EN) FRUCTOSYL PEPTIDYL OXIDASE AND SENSOR FOR ASSAYING A GLYCATED PROTEIN
(FR) NOUVELLE FRUCTOSYL PEPSIDYL OXYDASE
Abstract: front page image
(EN)Disclosed is the use of fructosyl peptidyl oxidase derived from a budding yeast Phaeosphaeria nodorum for assaying a glycated protein in a sample. The fructosyl peptidyl oxidase of the invention has higher activity toward fructosyl valine as well as fructosyl valyl histidine, and useful in assaying HbA1C with higher sensitivity and specificity. Electrode sensors comprising this enzyme are also disclosed.
(FR)Cette invention concerne l'utilisation d'un fructosyl peptidyl oxydase dérivée d'une levure de bourgeonnement Phaeosphaeria nodorum pour le criblage d'une protéine glycatée dans un échantillon. La fructosyl pepsidyl oxydase de l'invention à une activité supérieure à l'égard de la fructosyl vanine ainsi que de la fructosyl valyl histidine et convient pour le criblage de HbA1c avec une sensibilité et une spécificité supérieures.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)