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1. (WO2011014128) SMALL MOLECULE INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE WITH POTENTIAL ANTICANCER ACTIVITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/014128    International Application No.:    PCT/SG2010/000286
Publication Date: 03.02.2011 International Filing Date: 30.07.2010
Chapter 2 Demand Filed:    24.05.2011    
IPC:
C07D 209/14 (2006.01), C07D 209/24 (2006.01), A61K 31/4045 (2006.01), A61P 35/00 (2006.01)
Applicants: NATIONAL UNIVERSITY OF SINGAPORE [SG/SG]; 10 Kent Ridge Crescent Singapore 119260 (SG) (For All Designated States Except US).
LEOW, Jo Lene [MY/SG]; (SG) (For US Only).
CASEY, Mei-Wang [US/SG]; (SG) (For US Only).
CASEY, Patrick J [US/SG]; (SG) (For US Only).
GO, Mei Lin [SG/SG]; (SG) (For US Only).
SURESH, Kumar Gorla [IN/US]; (US) (For US Only)
Inventors: LEOW, Jo Lene; (SG).
CASEY, Mei-Wang; (SG).
CASEY, Patrick J; (SG).
GO, Mei Lin; (SG).
SURESH, Kumar Gorla; (US)
Agent: SCHIWECK, Wolfram; Viering, Jentschura & Partner LLP P.O. Box 1088 Rochor Post Office Rochor Road Singapore 911833 (SG)
Priority Data:
200905128-5 30.07.2009 SG
200907728-0 20.11.2009 SG
Title (EN) SMALL MOLECULE INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE WITH POTENTIAL ANTICANCER ACTIVITY
(FR) INHIBITEURS À PETITE MOLÉCULE D'ISOPRÉNYLCYSTÉINE CARBOXYL MÉTHYLTRANFÉRASE AVEC UNE ACTIVITÉ ANTICANCER POTENTIELLE
Abstract: front page image
(EN)The present invention generally relates to inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt), in particularly to compounds that inhibit Icmt activity and pharmaceutical compositions thereof. The invention also relates to methods of disease treatment using the same.
(FR)La présente invention porte d'une manière générale sur des inhibiteurs d'isoprénylcystéine carboxyl méthyltranférase (Icmt), en particulier sur des composés qui inhibent une activité Icmt et des compositions pharmaceutiques les comprenant. L'invention porte également sur des procédés de traitement de maladies les utilisant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)