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Pub. No.:    WO/2011/013735    International Application No.:    PCT/JP2010/062759
Publication Date: 03.02.2011 International Filing Date: 29.07.2010
Chapter 2 Demand Filed:    30.05.2011    
C07H 17/07 (2006.01), A61K 31/7048 (2006.01), A61P 31/04 (2006.01)
Applicants: NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY [JP/JP]; 1-1, Tsushima-Naka 1-chome, Kita-ku, Okayama-shi, Okayama 7008530 (JP) (For All Designated States Except US).
SASAKI, Kenji [JP/JP]; (JP) (For US Only).
TSUCHIYA, Tomofusa [JP/JP]; (JP) (For US Only).
Abugafar Md. Lokman Hossion [BD/JP]; (JP) (For US Only).
OHTSUKA, Nao [JP/JP]; (JP) (For US Only).
ZAMAMI, Yoshito [JP/JP]; (JP) (For US Only).
KUROSAKI, Yuji [JP/JP]; (JP) (For US Only)
Inventors: SASAKI, Kenji; (JP).
TSUCHIYA, Tomofusa; (JP).
Abugafar Md. Lokman Hossion; (JP).
ZAMAMI, Yoshito; (JP).
Agent: SHOJI, Takashi; 6F, 3-4-1, Higashi-nihonbashi, Chuo-ku, Tokyo 1030004 (JP)
Priority Data:
2009-178718 31.07.2009 JP
(JA) 新規フラバノン誘導体
Abstract: front page image
(EN)Disclosed is a novel antibacterial agent. Specifically disclosed is a novel antibacterial agent which can exert an effective action on various resistant bacteria such as VSSA, MRSA, VISA, VRE and VRSA. A novel flavanone derivative having a derivative of a 6-membered monosaccharide, in particular a glucose derivative or a galactose derivative, can exert an effective action on the aforesaid various bacteria. More specifically, a compound represented by formula (I) is disclosed. In formula (I), X represents a 6-membered monosaccharide derivative; and Y is substituted by a hydroxyl group.
(FR)Cette invention concerne un nouvel agent antibactérien. L'invention concerne précisément un nouvel agent antibactérien capable d'exercer une action efficace sur différentes bactéries résistantes comme VSSA, MRSA, VISA, VRE et VRSA. Un nouveau dérivé de flavanone comportant un dérivé d'un monosaccharide à 6 éléments, en particulier un dérivé du glucose ou un dérivé du galactose, peut exercer une action efficace sur les bactéries susmentionnées. L'invention concerne plus précisément un composé de formule (I). Dans la formule (I), X représente un dérivé monosaccharidique à 6 éléments; et Y est substitué par un groupe hydroxyle.
(JA)新規抗菌薬を提供する。より詳しくは、VSSAのほか、MRSA、VISA、VRE、VRSAなどの各種耐性菌に対しても有効に作用しうる新規抗菌薬を提供する。六員環の単糖類の誘導体、具体的にはグルコース誘導体又はガラクトース誘導体を有する新規フラバノン誘導体が、上記各種菌に対して有効に作用しうる。具体的には一般式Iの化合物による。 (式中、Xは六員環の単糖類の誘導体であり、Yが水酸基に置換されている。)
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)