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1. (WO2011013646) PHARMACEUTICAL PRODUCT FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2011/013646    International Application No.:    PCT/JP2010/062580
Publication Date: 03.02.2011 International Filing Date: 27.07.2010
IPC:
A61K 38/21 (2006.01), A01K 67/027 (2006.01), A61K 31/675 (2006.01), A61K 31/7048 (2006.01), A61P 21/00 (2006.01), A61P 25/00 (2006.01), A61P 43/00 (2006.01), C12N 15/09 (2006.01), G01N 33/15 (2006.01), G01N 33/50 (2006.01)
Applicants: THE UNIVERSITY OF TOKYO [JP/JP]; 3-1, Hongo 7-chome, Bunkyo-ku, Tokyo 1138654 (JP) (For All Designated States Except US).
KWAK Shin [JP/JP]; (JP) (For US Only).
YAMASHITA Takenari [JP/JP]; (JP) (For US Only).
HIDEYAMA Takuto [JP/JP]; (JP) (For US Only)
Inventors: KWAK Shin; (JP).
YAMASHITA Takenari; (JP).
HIDEYAMA Takuto; (JP)
Agent: SIKs & Co.; 8th Floor, Kyobashi-Nisshoku Bldg., 8-7, Kyobashi 1-chome, Chuo-ku, Tokyo 1040031 (JP)
Priority Data:
2009-175128 28.07.2009 JP
Title (EN) PHARMACEUTICAL PRODUCT FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
(FR) PRODUIT PHARMACEUTIQUE POUR LA PRÉVENTION ET LE TRAITEMENT DE LA SCLÉROSE LATÉRALE AMYOTROPHIQUE
(JA) 筋萎縮性側索硬化症の予防及び治療のための医薬
Abstract: front page image
(EN)Disclosed is a pharmaceutical product for prevention and treatment of sporadic amyotrophic lateral sclerosis, which contains, as an active ingredient, a substance that is selected from the group consisting of (a) leucomycins and oleandomycins, (b) cyclophosphamides, and (c) α interferons, said substance having an effect of activating ADAR2 activity in motor neuron.
(FR)L'invention porte sur un produit pharmaceutique pour la prévention et le traitement de la sclérose latérale amyotrophique sporadique, lequel produit contient, comme principe actif, une substance qui est choisie dans le groupe constitué par (a) les leucomycines et les oléandomycines, (b) les cyclophosphamides et (c) les interférons α, ladite substance ayant un effet d'activation de l'activité de l'ADAR2 dans les motoneurones.
(JA) 運動ニューロンにおけるADAR2活性賦活作用を有する(a)ロイコマイシン類及びオレアンドマイシン類、(b)シクロホスファミド類、並びに(c)インターフェロンα類からなる群から選ばれる物質を有効成分として含む孤発性筋萎縮性側索硬化症の治療及び/又は予防のための医薬。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)