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1. WO2011011783 - SPECTINAMIDES AS ANTI-TUBERCULOSIS AGENTS

Publication Number WO/2011/011783
Publication Date 27.01.2011
International Application No. PCT/US2010/043244
International Filing Date 26.07.2010
IPC
A61K 31/335 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
C07D 493/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
493Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
CPC
A61K 31/133
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
133having hydroxy groups, e.g. sphingosine
A61K 31/357
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
357having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
A61K 31/423
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
42Oxazoles
423condensed with carbocyclic rings
A61K 31/427
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
425Thiazoles
427not condensed and containing further heterocyclic rings
A61K 31/4409
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
4409only substituted in position 4, e.g. isoniazid, iproniazid
A61K 31/4433
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
4427containing further heterocyclic ring systems
4433containing a six-membered ring with oxygen as a ring hetero atom
Applicants
  • UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION [US]/[US] (AllExceptUS)
  • LEE, Richard, E. [GB]/[US] (UsOnly)
  • QI, Jianjun [CN]/[US] (UsOnly)
  • HURDLE, Juilian, G. [BB]/[US] (UsOnly)
  • MEIBOHM, Bernd [DE]/[US] (UsOnly)
  • VADDADY, Pavan, Kumar [IN]/[US] (UsOnly)
  • RAKESH (full legal name) [IN]/[US] (UsOnly)
  • LIU, Jiuyu [CN]/[US] (UsOnly)
Inventors
  • LEE, Richard, E.
  • QI, Jianjun
  • HURDLE, Juilian, G.
  • MEIBOHM, Bernd
  • VADDADY, Pavan, Kumar
  • RAKESH (full legal name)
  • LIU, Jiuyu
Agents
  • YANKWICH, Leon, R.
Priority Data
61/228,26624.07.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SPECTINAMIDES AS ANTI-TUBERCULOSIS AGENTS
(FR) SPECTINAMIDES EN TANT QU'AGENTS ANTITUBERCULEUX
Abstract
(EN)
Novel 3'-deoxy-3'-acylaminospectinomycin compounds are described. Also described are methods of using the 3'-deoxy-3-acylaminospectinomycin compounds and other spectinomycin analogs in treating tuberculosis and in treating microbial infections.
(FR)
La présente invention a pour objet de nouveaux composés de la 3'-désoxy-3'-acylaminospectinomycine. La présente invention concerne également des procédés d'utilisation des composés de la 3'-désoxy-3-acylaminospectinomycine et d'autres analogues de la spectinomycine dans le traitement de la tuberculose et dans le traitement des infections microbiennes.
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