Processing

Please wait...

Settings

Settings

Goto Application

1. WO2011011669 - METHODS AND COMPOSITIONS FOR DETECTION OF BIOLOGICAL MATERIALS USING MICROFLUIDIC DEVICES

Publication Number WO/2011/011669
Publication Date 27.01.2011
International Application No. PCT/US2010/043030
International Filing Date 23.07.2010
IPC
C12Q 1/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
C40B 30/04 2006.01
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
30Methods of screening libraries
04by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
CPC
B01L 3/502753
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502753characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
B01L 3/502776
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502769characterised by multiphase flow arrangements
502776specially adapted for focusing or laminating flows
G01N 33/54366
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54366Apparatus specially adapted for solid-phase testing
G01N 33/558
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
558using diffusion or migration of antigen or antibody
Applicants
  • UNIVERSITY OF WYOMING [US]/[US] (AllExceptUS)
  • CORCORAN, Robert C. [US]/[US] (UsOnly)
  • DUTTA, Debashis [IN]/[US] (UsOnly)
Inventors
  • CORCORAN, Robert C.
  • DUTTA, Debashis
Agents
  • BARONE, Stephen B.
Priority Data
61/228,06523.07.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS FOR DETECTION OF BIOLOGICAL MATERIALS USING MICROFLUIDIC DEVICES
(FR) PROCÉDÉS ET COMPOSITIONS POUR LA DÉTECTION DE MATÉRIAUX BIOLOGIQUES À L'AIDE DE DISPOSITIFS MICROFLUIDIQUES
Abstract
(EN)
Provided herein are microfluidic devices and methods useful for sensitive detection of analytes. The methods and devices described herein are also useful for detecting direct or indirect binding of enzymes or catalysts to a surface, for example a surface having analytes bound thereon. Methods disclosed herein include embodiments utilizing a pre-concentration scheme to improve signal levels of corresponding reporter moieties.
(FR)
L'invention porte sur des dispositifs microfluidiques et sur des procédés utiles pour une détection sensible d'analytes. Les procédés et dispositifs décrits présentement sont également utiles pour détecter une liaison directe ou indirecte d'enzymes ou catalyseurs à une surface, par exemple une surface ayant des analytes liés sur celle-ci. L'invention porte sur des procédés qui comprennent des modes de réalisation utilisant un schéma de préconcentration pour améliorer des niveaux de signal de fractions rapporteurs correspondantes.
Latest bibliographic data on file with the International Bureau